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Stoffwechselregulation in Durchfluß-systemen

II. Regulation zwischen Äthanolbildung und Speicherstoffwechsel bei Hefe während kontinuierlicher Substratzufuhr

Metabolic control in flow systems

II. Regulation of ethanol-synthesis and pool turnover in yeast under continuous substrate infusion

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Summary

The synthesis of ethanol under continuous infusion of d-glucose to anaerobic Saccharomyces carlsbergensis demonstrates very distinctly that turnover of the carbohydrate pool has the characteristics of a linear regulation, independent of the exogenous substrate amounts. The relation between glycolysis and pool turnover is balanced exctly so that 50–60% of glucose infused will be synthesized to ethanol.

Zusammenfassung

Am Beispiel der unter kontinuierlicher Substratzufuhr erfolgenden Äthanol-Synthese in Hefe (Saccharomyces carlsbergensis) konnte gezeigt werden, daß unabhängig von der exogenen Substratmenge der Speicherstoffwechsel einer linearen Regelfunktion unterliegt. Das Verhältnis zwischen Äthanolbildung aus exogenem und endogenem Material ist derart ausbalanciert, daß die Gesamtbilanz erhalten bleibt, nach der 50–60% der zugeführten Glucosemenge im Äthanol wiederzufinden sind.

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Literatur

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von Klitzing, L. Stoffwechselregulation in Durchfluß-systemen. Archiv. Mikrobiol. 72, 106–110 (1970). https://doi.org/10.1007/BF00409516

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  • DOI: https://doi.org/10.1007/BF00409516

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