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Gluconimycin, a new antibiotic

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Summary

A new antibiotic, gluconimycin, was isolated from Streptomyces AS 9. The systematic position of the organism is discussed. Gluconimycin has a polypeptide nature. It contains iron and gluconic acid in its molecule. Thus it has been classified as a member of sideromycins. Gluconimycin is considered from the fast moving type when chromatographed by butanolacetic acid-water. The antibiotic is active against Gram+ve, Gram-ve bacteria and some fungi. The antibiotic exerts high toxicity when injected in mice.

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References

  • Umezawa, H.: Recent advances in chemistry and biochemistry of antibiotics. Tokyo: Nissen Tosho Gusatau 1964.

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  • Waksman, S. A.: The Actinomycetes, vol. 2. Baltimore: Williams and Wilkins 1961.

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  • Zähner, H., R. Hütter u. E. Bachmann: Arch. Mikrobiol. 36, 395 (1960).

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Authors and Affiliations

  1. Biochemistry Dept., Faculty of Science, Ain Shams University, Cairo

    Ibrahim R. Shimi & Ahmed Dewedar

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  1. Ibrahim R. Shimi
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  2. Ahmed Dewedar
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Shimi, I.R., Dewedar, A. Gluconimycin, a new antibiotic. Archiv. Mikrobiol. 54, 246–252 (1966). https://doi.org/10.1007/BF00408997

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  • DOI: https://doi.org/10.1007/BF00408997

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