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Depigmentation due to para tertiary butyl catechol

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Summary

A 49-year-old man developed occupational leucoderma after the contact with para tertiary butyl catechol. He was a worker in a polyester resin plant. Allergic reaction was found at the patch test site with p-TBC and depigmentation was induced at the site. A cross reaction to para tertiary butyl phenol was also observed.

Histologically, the depigmented lesion revealed decreased number of melanin and DOPA-positive melanocytes in the basal layer.

The mechanism of depigmentation was discussed.

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Authors and Affiliations

  1. Department of Dermatology, Faculty of Medicine, Kyoto University, Yoshidakonoecho, 606, Kyoto, Japan

    Takeshi Horio M.D., Ken-ichi Tanaka M.D. & Jinro Komura M.D.

Authors
  1. Takeshi Horio M.D.
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  2. Ken-ichi Tanaka M.D.
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  3. Jinro Komura M.D.
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Horio, T., Tanaka, Ki. & Komura, J. Depigmentation due to para tertiary butyl catechol. Int. Arch Occup Environ Heath 39, 127–133 (1977). https://doi.org/10.1007/BF00405657

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  • DOI: https://doi.org/10.1007/BF00405657

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