Summary
Delay of punishment 0, 30, 60, 120 and 240 sec after the step-through response in a one trial passive avoidance task was used to obtain in mice conditioned responses of different strengths. Both cycloheximide and ECS given immediately after training had a greater amnesic effect upon the weaker conditioned responses obtained with the longer delays of punishment. A proactive effect of ECS, but not of cycloheximide, was demonstrated with the weaker conditioned responses.
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Geller, A., Robustelli, F. & Jarvik, M.E. A parallel study of the amnesic effects of cycloheximide and ECS under different strengths of conditioning. Psychopharmacologia 16, 281–289 (1970). https://doi.org/10.1007/BF00404734
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DOI: https://doi.org/10.1007/BF00404734