Summary
Electron-microscopic investigations of the condyloma acuminatum show different nuclear inclusions in keratinocytes of the granular layer or the layer immediately below. Fibrous structures were indentified as tonofilaments and irregularly shaped electron-dense substances as keratohyalin. However the question remains as to whether there is a connection between the viral infection and the occurrence of such intranuclear inclusions.
Zusammenfassung
Beim Condyloma acuminatum lassen sich bei elektronen-mikroskopischer Untersuchung in Keratinocyten des Stratum granulosum bzw. unmittelbar darunter unterschiedliche Kerneinschlüsse beobachten. Fibrilläre Strukturen halten wir für Tonofilamente, unregelmäßig geformte elektronendichte, granuläre Substanzen für keratohyalin. Die Frage, ob ein Zusammenhang zwischen der Virusinfektion und dem Auftreten solcher intranukleärer Einschlüsse besteht, bleibt zu diskutieren.
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Führer, R., Klingmüller, G. Nuclear inclusions of tonofilaments and keratohyalin granules in the condyloma acuminatum. Arch Dermatol Res 269, 69–74 (1980). https://doi.org/10.1007/BF00404459
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DOI: https://doi.org/10.1007/BF00404459