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Scopolamine, atropine and conditioned fear

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Summary

Two experiments, designed to determine the effects of anticholinergics on fear-conditioning, are reported. The results indicate that scopolamine and atropine were not effective in reducing the conditioning of fear. These experiments indicate that previous findings suggestive of attenuated habituation with the antichiolnergics, cannot reasonable be accounted for in terms of a general memory deficit. Other data pertinent to this finding are discussed.

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Research supported by Public Health Service grant MH-08585.

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Vogel, J.R., Hughes, R.A. & Carlton, P.L. Scopolamine, atropine and conditioned fear. Psychopharmacologia 10, 409–416 (1967). https://doi.org/10.1007/BF00403981

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