Summary
Intracutaneous injection of Varicella-zoster (V-Z) viral antigen was performed on 55 patients with herpes zoster. All of them reacted positively after 10 days. The patients in the acute stage responded weakly whereas those in the convalescent phase developed a stronger reaction. The intensity of the reaction did not correlate with the number of days of illness. Positive reactions were observed in those patients who had suffered from herpes zoster several years ago. Complement fixing antibody titers did not parallel the intensity of skin reaction.
Zusammenfassung
Varicella-Zoster-Antigen wurde i.c. 55 Patienten mit Herpes zoster injiziert. Nach 10 Tagen entwickelte sich bei allen Patienten eine positive Reaktion. Bei Patienten im akuten Stadium war die Reaktion schwach. Bei Patienten in der Erholungsphase zeigte sich eine verstärkte Reaktion. Die Intensität der Reaktion war nicht mit den Krankheitstagen korreliert. Positive Reaktionen zeigten sich auch in einem Kollektiv, das einige Jahre zuvor den Herpes zoster überstanden hatte. Antikörpertiter zeigten keine Parallelität zur Stärke der Hautreaktion.
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Hata, S. Skin test with Varicella-zoster virus antigen on herpes zoster patients. Arch Dermatol Res 268, 65–70 (1980). https://doi.org/10.1007/BF00403887
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DOI: https://doi.org/10.1007/BF00403887