Skip to main content
SpringerLink
Log in

Activity and learning in rats after magnesium pemoline

  • Short Communications
  • Published:
Psychopharmacologia Aims and scope Submit manuscript

Summary

Manesium pemoline enhances the learning of a conditioned avoidance response in rats. 24 hours later this enhancing effect is no longer significant. With the same doses, magnesium pemoline induces a marked hyperactivity. In an experimental situation of simple visual discrimination magnesium pemoline does not alter the performance of the animals but seems to bring about an abnormal fixation of certain types of behaviour.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Beach, G., and D. P. Kimble: Activity and responsivity in rats after Magnesium Pemoline injections. Science 155, 698–701 (1967).

    PubMed  Google Scholar 

  • Cardo, B.: Rapports entre le niveau de vigilance et le conditionnement chez l'animal. Etude pharmacologique et neurologique. J. Physiol. (Paris) 53, no 3 (Suppl.), 1–212 (1961).

    Google Scholar 

  • Krechevsky, I.: “Hypotheses” in rats. Psyohol. Rev. 39, 516–532 (1932).

    Google Scholar 

  • Lange, W. E., B. H. Candon, and M. Chessin: Metal chelates of oxazolidinones as central nervous system stimulants. J. pharm. Sci. 51, 477–480 (1962).

    PubMed  Google Scholar 

  • Plotnikoff, N.: Magnesium pemoline: Enhancement of learning and memory of a conditioned avoidance response. Science 151, 703–704 (1966).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculté des Sciences, Laboratoire de Psychophysiologie, 20, Cours Pasteur, F-33 Bordeaux

    B. Soumireu-Mourat & B. Cardo

Authors
  1. B. Soumireu-Mourat
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B. Cardo
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Soumireu-Mourat, B., Cardo, B. Activity and learning in rats after magnesium pemoline. Psychopharmacologia 12, 258–262 (1968). https://doi.org/10.1007/BF00403780

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00403780

Keywords

Search

Navigation