Summary
The effect of nicotinamide adenine dinucleotide (NAD) upon the response rates in variable interval and Sidman Avoidance schedules was studied in rats. Bar pressing on the variable interval reinforcement schedule was significantly reduced during the 15 min following the administration of 10 mg/kg i.p. and during the 60 min following the administration of 30 mg/kg NAD. Response rates on the Sidman Avoidance schedule were significantly reduced during the 60 min following the administration of 100 mg/kg NAD.
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Layden, T.A., McGrath, W.R. & Smith, F.D. Psychopharmacological action of nicotinamide adenine dinucleotide. Psychopharmacologia 17, 198–202 (1970). https://doi.org/10.1007/BF00402710
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DOI: https://doi.org/10.1007/BF00402710