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Psychopharmacologia

, Volume 18, Issue 1, pp 108–117 | Cite as

Psychological studies of marijuana and alcohol in man

  • Reese T. Jones
  • George C. Stone
Original Investigations

Abstract

Regular users of marijuana (cannabis sativa) were given smoked and orally administered marijuana, a placebo, or alcohol. They were unable to distinguish between smoked marijuana and the tetrahydrocannabinol-free placebo. The oral administration of tincture of cannabis produced primarily dysphoric symptoms and was similar to alcohol in this respect. The smoked marijuana altered pulse rate, time estimation, and EEG, but had no effect on a measure of field dependence or on a digit symbol substitution task. Both drugs appeared to be mild intoxicants in a laboratory setting. Consideration of the dose, prior experience with drugs, setting, and possible cross tolerance of marijuana and alcohol are important in evaluating the significance of the clinical effects.

Key-Words

Cannabis (Marijuana) Alcohol Psychopharmacology Placebos Drug Abuse 

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Copyright information

© Springer-Verlag 1970

Authors and Affiliations

  • Reese T. Jones
    • 1
    • 2
  • George C. Stone
    • 1
    • 2
  1. 1.Langley Porter Neuropsychiatric InstituteSan Francisco
  2. 2.School of MedicineUniversity of CaliforniaSan Francisco

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