Skip to main content
Log in

Swimming perfomance of mice as affected by antidepressant drugs and baseline levels

  • Original Investigations
  • Published:
Psychopharmacologia Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Bättig, K.: Die Wirkung von Training und Amphetamin auf Ausdauer und Geschwindigkeit der Schwimmleistung der Ratte. Psychopharmacologia (Berl.) 4, 15–27 (1963).

    Google Scholar 

  • —: Das Schwimmen von Ratten durch einen Wasserkanal. Methodische und pharmakologische Einflüsse auf Leistung und Ermüdung. Helv. physiol. pharmacol. Acta 19, 384–398 (1961).

    PubMed  Google Scholar 

  • Brodie, B. B., M. H. Bickel, and F. Sulser: Desmethylimipramine, a new type of antidepressant drug. Med. exp. (Basel) 5, 454–458 (1961).

    Google Scholar 

  • Cook, L., and R. T. Kelleher: Drug effects on the behavior of animals. Ann. N. Y. Acad. Sci. 96, 315–335 (1962).

    PubMed  Google Scholar 

  • Dews, P. B.: A behavioral output enhancing effect of imipramine in pigeons. Int. J. Neuropharmacol. 1, 265–272 (1962).

    Google Scholar 

  • Dimascio, A., G. Heninger, and G. L. Klerman: Psychopharmacology of imipramine and desipramine: A comparative study of their effects in normal males. Psychopharmacologia (Berl.) 5, 361–371 (1964).

    Google Scholar 

  • Edwards, A. L.: Experimental design in psychological research. New York: Rinehart and Co. Inc. 1960.

    Google Scholar 

  • Furgiuele, A. R., W. J. Kinnard, and J. P. Buckley: Central effects of B-phenylisoprophylhydrazine and iproniazid. J. Pharmacol. exp. Ther. 137, 356–360 (1962).

    PubMed  Google Scholar 

  • Gilette, J. R., J. V. Dingell, F. Sulser, R. Kuntzman, and B. B. Brodie: Isolation from rat brain of a metabolic product, desmethylimipramine, that mediates the antidepressant activity of imipramine (Tofranil). Experientia (Basel) 17, 417–419 (1961).

    Google Scholar 

  • Heise, G. A., and E. Boff: Behavioral determination of time and dose parameters of monoamine oxidase inhibitors. J. Pharmacol. exp. Ther. 129, 155–162 (1960).

    PubMed  Google Scholar 

  • Irwin, S., M. Slabok, and G. Thomas: Individual differences. I. Correlation between control locomotor activity and sensitivity to stimulant and depressant drug. J. Pharmacol. exp. Ther. 123, 206–211 (1958).

    PubMed  Google Scholar 

  • Jacobs, J., et G. Michaud: Actions de divers agents pharmacologiques sur les temps depuisement et le comportement de souris nageant a 20° C. Arch. int. Pharmacodyn. 133, 101–115 (1961).

    PubMed  Google Scholar 

  • Kay, H., and J. E. Birren: Swimming speed of the albino rat. J. Geront. 13, 378–385 (1958).

    PubMed  Google Scholar 

  • Kornetsky, C.: A comparison of the effects of desipramine and imipramine on two schedules of reinforcement. Int. J. Neuropharmacol. 4, 13–16 (1965).

    Google Scholar 

  • -, J. Dawson, and E. Pelikan: Individual animal variation in the effects of pentobarbital and dextro-amphetamine (a comparison). In M. Finkel (ed.): Specific and Non-Specific Factors in Psychopharmacology, pp. 161–171. New York: Philosophical Library.

  • Lapin, I. P.: Comparison of imipramine and chlorpromazine effects on behavior of amphetamine-excited animals. In Z. Votava, M. Horvath and O. Vinar (Eds.): Psychopharmacological Methods, pp. 80–86. New York: The Macmillan Co. 1963.

    Google Scholar 

  • Latz, A., C. Kornetsky, and G. Bain: The effects of d-amphetamine on discrete avoidance as a function of the pre-drug level of performance. Fed. Proc. 24, 197 (1965).

    Google Scholar 

  • Otis, L., and J. Bosley: Animal behavior. In Drug Enhancement of Performance, pp. IV-5 IV–42. Menlo Park, California: Stanford Research Institute, 1960.

    Google Scholar 

  • Randall, L. O., and R. E. Bagdon: Pharmacology of iproniazid and other amine oxidase inhibitors. Ann. N.Y. Acad. Sci. 80, 626–642 (1959).

    PubMed  Google Scholar 

  • Sigg, E. B.: The pharmacodynamics of imipramine. In J. H. Nodine and J. H. Moyer (Eds.): Psychomatic Medicine, pp. 671–678. Philadelphia: Lea and Febiger 1962.

    Google Scholar 

  • Smith, G. M., and H. K. Beecher: Amphetamine sulfate and athletic performance. I. Objective effects. J. Amer. med. Ass. 170, 542–557 (1959).

    Google Scholar 

  • Stein, L.: New methods for evaluating stimulants and antidepressants. In J. H. Nodine and J. H. Moyer (eds.): Psychomatic Medicine, pp. 297–311. Philadelphia: Lea and Febiger 1962.

    Google Scholar 

  • Sulser, F., J. Watts, and B. B. Brodie: On the mechanism of antidepressant action of imipramine-like drugs. Ann. N.Y. Acad. Sci. 96, 279–286 (1962).

    PubMed  Google Scholar 

  • Wilberg, C. G., and J. B. Hunn: Swimming of albino mice. J. appl. Physiol. 15, 704–705 (1960).

    PubMed  Google Scholar 

  • Woods, P. J., E. H. Davidson, and R. J. Peters: Instrumental escape conditioning in a water tank: effects of variation in drive stimulus intensity and reinforcement magnitude. J. comp. physiol. Psychol. 57, 466–470 (1964).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

This research was supported in part by Public Health Service Research Grant PHS MH-03312.

Work done while senior author held a Postdoctoral Fellowship No. 2-F2-MH-16,931-02 from the USPHS and a Research Fellowship from the Medical Foundation, Inc. of Boston.

NIH Career Development Awardee GM-K3-1759.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Latz, A., Kornetsky, C., Bain, G. et al. Swimming perfomance of mice as affected by antidepressant drugs and baseline levels. Psychopharmacologia 10, 67–88 (1966). https://doi.org/10.1007/BF00401900

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00401900

Keywords

Navigation