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Effect of hashish smoke sublimate on hypothalamic noradrenaline studied by the fluorescence method

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Abstract

A histochemical study with the fluorescence method showed that administration of cannabis sublimate administered to rats increased the noradrenaline content of the terminal axonal varicosities of the hypothalamus, probably caused by a facilitation of noradrenaline uptake. The findings are discussed in relation to other known effects of cannabis derivatives, hypothermia, increased appetite and prolongation of amphetamine action.

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Authors and Affiliations

  1. Department of Psychiatry, University of Geneva, 1225, Bel-Air, Switzerland

    J. Constantinidis

  2. Department of Biological Chemistry, University of Athens, Greece

    C. J. Miras

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  1. J. Constantinidis
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  2. C. J. Miras
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Constantinidis, J., Miras, C.J. Effect of hashish smoke sublimate on hypothalamic noradrenaline studied by the fluorescence method. Psychopharmacologia 22, 80–90 (1971). https://doi.org/10.1007/BF00401470

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  • DOI: https://doi.org/10.1007/BF00401470

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