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A study of the alcohol-tolerance effect and an introduction of a new behavioural technique


The alcohol-tolerance effect was studied with 12 male white rats. A two-turn task in a temporal circular maze, which possesses some advantageous features for behavioural drug studies, was used as a behavioural technique. The results show that Ss that had the repeated opportunities for running the maze while under the influence of alcohol perform much better than Ss that had merely been accustomed to alcohol but trained in a sober state. This result suggests that the tolerance effect could not be accounted for entirely in terms of physio-biochemical mechanisms, some behavioural principles may need to be invoked.

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  1. Chen, C. S.: Training schedule in a two-turn task in a temporal circular maze. Psychon. Sci. 9, 273–274 (1967).

    Google Scholar 

  2. —: Can rats count? Nature (Lond.) 214, 15–17 (1967a).

    Google Scholar 

  3. Laties, V. G., and B. Weiss: Effects of alcohol on timing behaviour. J. comp. physiol. Psychol. 55, 85–91 (1962).

    PubMed  Google Scholar 

  4. Reynolds, G. S., and P. van Sommers: Effects of ethyl alcohol on avoidance behaviour. Science 132, 42–43 (1960).

    Google Scholar 

  5. Rushton, R., and H. Steinberg: Modification of behavioural effects of drugs by past experience. In H. Steinberg, A. V. S. de Reuck and J. Knight (Eds.): Animal Behaviour and Drug Action, pp. 207–233 (1964).

  6. — —, and C. Tinson: Effects of a single experience on subsequent reactions to drugs Brit. J. Pharmacol. 20, 99–105 (1963).

    PubMed  Google Scholar 

  7. Sidman, M.: Technique for the assessment of drug effects on timing behaviour. Science 122, 925 (1955).

    PubMed  Google Scholar 

  8. Siegel, S.: Nonparametric Statistics for the Behavioural Science. New York: McGraw-Hill 1956.

    Google Scholar 

  9. Trotter, J. R.: The physical properties of bar-pressing behaviour and the problem of reactive inhibition. Quart. J. exp. Psychol. 8, 97–106 (1956).

    Google Scholar 

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A. N. U. Postgraduate research scholar. I thank Dr. J. R. Trotter and Mr. B. Thorley for reading the manuscript and for discussions, and Professor C. A. Gibb for his encouragement and for the facilities of his department.

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Chen, CS. A study of the alcohol-tolerance effect and an introduction of a new behavioural technique. Psychopharmacologia 12, 433–440 (1968).

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  • Alcohol
  • Tolerance in Animals' Maze