Summary
The computed tomographic morphology of malignant choroidal melanoma and its perfusion characteristics are described. Thirty-three static and serial CT examinations made on 29 patients with choroidal melanoma, three with pseudotumors of the macula and one with choroidal metastasis revealed the choroidal melanoma to be usually a hyperdense, markedly perfused tumor, while the non-contrast, diagnostically undifferentiable pseudotumors and the choroidal metastasis, revealed no significant change in density after the administration of contrast material. Density values or perfusion characteristics of choroidal melanoma that are outside of the normal range are a result of secondary changes within the immediate surroundings of the tumor, such as detachment of the retina, tumor-induced glaucoma, or tumor necrosis.
Similar content being viewed by others
References
Wende S, Aulich A (1976) Die Computer-Tomographie der Orbita. In: Ullerich K (Hrsg) Die gezielte Diagnostik raumfordernder Prozesse der Orbita. Enke, Stuttgart, S 28–42
Wollensak J, Bleckmann H, Lange S, Grumme T (1976) Computertomographie des Auges und der Orbita. Klin Monatsbl Augenheilkd 168:467–475
Wende S, Aulich A, Nover A, Lanksch W, Kazner E, Steinhoff H, Meese W, Lange S, Grumme T (1977) Computed tomography of orbital lesions. Neuroradiology 13:123–134
Salvolini U, Menichelli F, Pasquini U (1977) Computer assisted tomography in 90 cases of exophthalmos. J Comput Assist Tomogr 1:81–100
Hilal SK, Trokel SL (1977) Computerized tomography of the orbit using thin sections. Semin Roentgenol 12:137–147
Gyldensted C, Lester J, Fledelius H (1977) Computed tomography of orbital lesions. Neuroradiology 13:141–150
Wiggly U (1979) Computertomographie der Orbita. Klin Monatsbl Augenheilkd 174:799–805
Jacobs W, Weisberger A, Kinkel WR (1980) Computerized tomography of the orbit and sella turcica. Raven Press, New York, pp 281–292
Nadjmi M, Piepgras U, Vogelsang H (1981) Kranielle Computertomographie. Nadjmi M (Hrsg) Thieme, Stuttgart New York, S 421–445
Kazner E, Wende S, Grumme T, Lanksch W, Stochdorph O (1981) Computertomographie intrakranieller Tumoren aus klinischer Sicht. Springer, Berlin Heidelberg New York, S 463–502
Naumann GOH (1980) Pathologie des Auges. Springer, Berlin Heidelberg New York, S 408–500
Bigar F, Spiess H, Gruber HU (1979) Kombinierte Anwendung der Computertomographie und Echographie in der Ophthalmologie. Klin Monatsbl Augenheilkd 174:806–815
Guthoff R (1980) Modellmessungen zur Volumenbestimmung des malignen Aderhautmelanoms. Albrecht Von Graefes Arch Klin Exp Ophthalmol 214:139–146
van Damme W, Kosmann P, Wackenheim C (1977) A standardized method for computed tomography of the orbits. Neuroradiology 13:139–140
Heller M, Grabbe E, Bücheler E (1981) Serien-Computer-tomographie-Methodik und erste Erfahrungen. RÖFO 134:16–21
Heller M, Jend H-H, Grabbe E, Hambüchen K (1981) Dynamic computed tomography. Electromedica 2:68–73
Drayer BP, Heinz ER, Dujovny M, Wolfson SK, Gur D (1979) Patterns of brain perfusion: dynamic computed tomography using intravenous contrast enhancement. J Comput Assist Tomogr 3:633–640
Guthoff R, Heller M, Hallermann D, Hagemann J (1981) Erste Erfahrungen mit der Seriencomputertomographie beim malignen Melanom der Aderhaut. Ophthalmologica 183:154–161
Newton TH, Watanabe T, LaMasters D, Turski P (1981) Contrast enhancement of the orbit. 4th International Symposium on Orbital Disorders, Amsterdam
Shields JA, Augsburger JJ (1981) The management of orbital extension of uveal melanomas. 4th International Symposium on Orbital Disorders, Amsterdam
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Heller, M., Guthoff, R., Hagemann, J. et al. CT of malignant choroidal melanoma—morphology and perfusion characteristics. Neuroradiology 23, 23–30 (1982). https://doi.org/10.1007/BF00399701
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00399701