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Serial cytogenetic analysis in a patient with pseudodiploid bladder cancer

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Summary

Chromosome analysis with G- and C-banding was performed four times on a recurrent non-invasive transitional cell carcinoma of the urinary bladder. Persistence of a pseudodiploid karyotype with four markers was found in each specimen. Therefore, it is suggested that the presence of chromosome aberration may be related to the recurrences of urinary bladder carcinomas.

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References

  • Falor WH, Ward RM (1978) Prognosis in early carcinoma of the bladder based on chromosomal analysis. J Urol 119:44–48

    PubMed  Google Scholar 

  • Fossa SD (1977) DNA-variations in neighbouring epithelium in patients with bladder carcinoma. Acta Path Microbiol Immunol Scand [A] 85:603–610

    Google Scholar 

  • Granberg-Öhman I, Tribukait B, Wijkström H, Berlin T, Collste L (1980) Papillary carcinoma of the urinary bladder. A study of chromosomal and cytophotometric DNA analysis. Urol Res 8:87–93

    Article  PubMed  Google Scholar 

  • Granberg-Öhman I, Tribukait B, Wijkström H (1984) Cytogenetic analysis of 62 transitional cell bladder carcinomas. Cancer Genet Cytogenet 11:69–85

    Article  PubMed  Google Scholar 

  • Høstmark JG, Laerum OD, Farsund T (1984) DNA aberrations of bladder mucosa in patients with transitional cell carcinomas. Scand J Urol Nephrol 18:113–120

    PubMed  Google Scholar 

  • Sandberg AA (1981) Chromosome studies in bladder cancer. In: Connolly JG (ed) Carcinoma of the bladder. Raven Press, New York, pp 127–141

    Google Scholar 

  • Soloway MS, Murphy W, Rao MK, Cox C (1978) Serial multiple-site biopsies in patients with bladder cancer. J. Urol 20:57–59

    Google Scholar 

  • Summers JL, Falor WH, Ward R (1981) A 10-year analysis of chromosomes in non-invasive papillary carcinoma of the bladder. J Urol 125:177–178

    PubMed  Google Scholar 

  • Summers JL, Coon JS, Ward RM, Falor WH, Miller AW, Weinstein RS (1983) Prognosis in carcinoma of the urinary bladder based upon tissue blood ABH and Thomsen-Friedenreich antigen status and karyotype of the initial tumor. Cancer Res 43:934–939

    PubMed  Google Scholar 

  • Trent JM, Stanisic T, Olson S (1984) Cytogenetic analysis of urologic malignancies: study of tumor colony forming cells and premature chromosome condensation. J Urol 131:146–151

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Laboratory of Cytogenetics, Institute of Pathology, Medical School Hannover, P.O. Box 610140, D-3000, Hannover, Federal Republic of Germany

    G. Kovacs

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  1. G. Kovacs
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Supported by the Deutsche Forschungsgemeinschaft (DFG-Ko 841/1-1)

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Kovacs, G. Serial cytogenetic analysis in a patient with pseudodiploid bladder cancer. J Cancer Res Clin Oncol 110, 249–251 (1985). https://doi.org/10.1007/BF00399284

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  • DOI: https://doi.org/10.1007/BF00399284

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