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Soft tissue sarcoma as second malignant lesion after therapy for Hodgkin's disease

Report of two cases and review of the literature

  • Original Papers
  • Clinical Oncology or Epidemiology
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Summary

Two cases of soft tissue sarcoma following treatment of nodular sclerosing Hodgkin's disease are described. One patient developed a malignant schwannoma after radiotherapy, the other was diagnosed as having a malignant fibrous histiocytoma after treatment with radiation and chemotherapy. Both secondary malignancies arose within the irradiated field after a latent period rangig from 9.5 years in the first to 21 years in the second case. A review of the pertinent literature is given and previous reports of malignant tumors and leukemias following therapy for Hodgkin's disease are summarized.

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Authors and Affiliations

  1. Institut für Pathologie, Klinikum der Christian-Albrechts-Universität, Hospitalstr. 42, D-2300, Kiel I, Federal Republic of Germany

    G. H. Griesser & M.-L. Hansmann

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  1. G. H. Griesser
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  2. M.-L. Hansmann
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Griesser, G.H., Hansmann, ML. Soft tissue sarcoma as second malignant lesion after therapy for Hodgkin's disease. J Cancer Res Clin Oncol 110, 238–243 (1985). https://doi.org/10.1007/BF00399281

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  • DOI: https://doi.org/10.1007/BF00399281

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