Summary
A solo δ sequence flanking the 5′ end of the ADHII structural gene, ADR2, can promote a number of DNA rearrangements some of which were investigated in detail. In a selective system haploid mutants were screened in which a solo S sequence flanking ADR2 had been joined to a Ty element. Three different types of events can create such a structure: Reintegration of a Ty sequence at the δ-ADR2 site, inversion of ADR2 and flanking material, and transposition of ADR2 along with 3′ flanking material. The involvement of reciprocal or non-reciprocal exchange mechanisms in creating such events are discussed.
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Ciriacy, M., Breilmann, D. δ Sequences mediate DNA rearrangements in Saccharomyces cerevisiae . Curr Genet 6, 55–61 (1982). https://doi.org/10.1007/BF00397642
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DOI: https://doi.org/10.1007/BF00397642