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Leukotriene antagonists prevent endotoxin lethality

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We are indebted to P. Sheard (Fisons Pharmaceuticals) for the gift of FPL 55712, to Dr. C. Galanos for samples of purified LPS from S. abortus equi, and to Lederle/Cyanamid for providing diethylcarbamazine. We gratefully acknowledge the excellent assistance of C. Forsthove and the help in the animal experiments by K. Happersberger. This work was supported by the Deutsche Forschungsgemeinschaft, Bonn, through Forschergruppe “Leber”, Freiburg im Breisgau.

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Hagmann, W., Keppler, D. Leukotriene antagonists prevent endotoxin lethality. Naturwissenschaften 69, 594–595 (1982). https://doi.org/10.1007/BF00396357

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