Summary
Heteroclass chick/mouse chimaeras were prepared by transplanting somitic presumptive myogenic cells or limb bud myoblasts from donor mouse embryos into chick hosts, to replace (1) previously extirpated brachial somitic mesoderm or (2) experimentally deleted limb premuscular masses. Since mouse and chick cells can be distinguished by differential staining affinities, this parameter was used to verify the viability of the implant and to assess its fate. Our analyses showed that transplanted mouse somitic myogenic stem cells or limb bud myoblasts did not participate in the host brachial musculature, whatever the experimental conditions.
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References
Agnish ND, Kochhar M (1977) The role of somites in the growth and early development of mouse limb buds. Dev Biol 56:174–183
Armand O, Boutineau AM, Mauger A, Pautou MP, Kieny M (1983) Origin of satellite cells in avian skeletal muscles. Arch Anat Microsc Morphol Exp 72:163–181
Bonner PH, Hauschka SD (1974) Clonal analysis of vertebrate myogenesis. I. Early developmental events in the chick limb. Dev Biol 37:317–328
Cauwenbergs P, Butler J, Cosmos E (1986) Intraspecific chick/chick chimaeras: dystrophic somitic mesoderm transplanted to a normal host forms muscles with a dystrophic phenotype. Neurosci Lett 68:149–154
Chevallier A (1978) Etude de la migration des cellules somitiques dans le mésoderme somatopleural de l'ébauche de l'aile. Wilhelm Roux's Arch 184:57–73
Chevallier A, Kieny M (1982) On the role of the connective tissue in the patterning of the chick limb musculature. Wilhelm Roux's Arch 191:277–280
Chevallier A, Kieny M, Mauger A (1976) Sur l'origine de la musculature de l'aile chez les oiseaux. CR Acad Sci (Paris) Série D 282:309–311
Chevallier A, Kieny M, Mauger A (1977) Limb-somite relationship: origin of the limb musculature. J Embryol Exp Morphol 41:245–258
Chevallier A, Kieny M, Mauger A (1978) Limb-somite relationship: effect of removal of somitic mesoderm on the wing musculature. J Embryol Exp Morphol 43:263–278
Chevallier A, Pautou MP, Harris AJ, Kieny M (1987) On the non-equivalence of skeletal muscle satellite cells and embryonic myoblasts. Arch Anat Microsc Morphol Exp (in press)
Christ B, Cihak R (1986) Development and regeneration of skeletal muscles. Karger, Basel, pp 1–221
Christ B, Jacob HJ, Jacob M (1977) Experimental analysis of the origin of the wing musculature in avian embryos. Anat Embryol 150:171–186
Cunha GR, Vanderslice KD (1984) Identification in histological sections of species origin of cells from mouse, rat and human. Stain Technology 59:1–12
Dhouailly D, Sengel P (1972) La morphogenèse de la plume et du poil, étudiée par des associations hétérospécifiques de derme et d'épiderme entre le Poulet et la Souris. CR Acad Sc (Paris) Série D 275:479–482
Dhouailly D, Sengel P (1983) Feather forming properties of the foot integument in avian embryos: In: Sawyer RH, Fallon JF (eds) Epitheliomesenchymal Interactions in Development. Praeger Publishers, New York, pp 147–162
Feulgen R, Rossenbeck H (1924) Mikroskopisch-chemischer Nachweis einer Nucleinsäure vom Typus der Thymonucleinsäure und die darauf beruhende elektive Färbung von Zellkernen in mikroskopischen Präparaten. Hoppe-Seyler's Z Physiol Chem 135:203–252
Gumpel-Pinot M (1974) Contribution du mésoderme somitique à la genèse du membre chez l'embryon d'oiseau. CR Acad Sci (Paris) Série D 278:1305–1308
Gumpel-Pinot M, Ede DA, Flint OP (1984) Myogenic cell movement in the developing avian limb bud in presence and absence of the apical ectodermal ridge (AER). J Embryol Exp Morphol 80:105–125
Hamburger V, Hamilton HL (1951) A series of normal stages in the development of the chick embryo. J Morphol 88:49–92
Houben JJG (1976) Aspects ultrastructuraux de la migration de cellules somitiques dans les bourgeons de membres postérieurs de souris. Arch Biol (Bruxelles) 87:345–365
Jacob M, Christ B, Jacob HJ (1978) On the migration of myogenic stem cells into the prospective wing region of chick embryos. A scanning and transmission electron microscopy study. Anat Embryol 153:179–193
Kieny M (1980) The concept of a myogenic cell line in developing avian limb bud. In: Merker HJ, Nau H, Hebert D (eds) Teratology of the Limbs. W de Gruyter, Berlin, New York, pp 79–89
Kieny M, Chevallier A (1979) Autonomy of tendon development in the embryonic chick wing. J Embryol Exp Morphol 49:153–165
Kieny M, Mauger A, Hedayat I, Goetinck PF (1983) Ontogeny of the leg muscle tissue in the crooked neck dwarf mutant (cn/cn) chick embryo. Arch Anat Micr Morphol Exp 72:1–17
Kieny M, Pautou MP, Chevallier A, Mauger A (1986) Spatial organization of the developing limb musculature in birds and mammals. Bibl Anat 29:65–90
Le Douarin N, Barq G (1969) Sur l'utilisation des cellules de caille japonaise comme “marqueurs biologiques” en embryologie expérimentale. CR Acad Sci (Paris) Série D 269:1543–1546
Lewis JH, Chevallier A, Kieny M, Wolpert L (1981) Muscle nerve branches do not develop in chick wings devoid of muscle. J Embryol Exp Morphol 64:211–232
Noden DM (1983) The embryonic origins of avian cephalic and cervical muscles and associated connective tissues. Am J Anat 168:257–276
Noden DM (1986) Patterning of avian craniofacial muscles. Dev Biol 116:347–356
Mauger A (1972) Rôle du tube neural dans le développement du plumage dorsal de l'embryon de Poulet. Wilhelm Roux's Arch 170:244–266
Mauger A, Kieny M, Hedayat I, Goetinck PF (1983) Tissue interactions in the organization and maintenance of the muscle pattern in the avian limb. J Embryol Exp Morphol 76:199–215
Milaire J (1976) Contribution cellulaire des somites à la genèse des bourgeons de membres postérieurs chez la souris. Arch Biol (Bruxelles) 87:315–343
Moscona A (1957) The development in vitro of chimeric aggregates of dissociated embryonic chick and mouse cells. Proc Natl Acad Sci (USA) 43:184–194
Newman S, Pautou MP, Kieny M (1981) The distal boundary of myogenic primordia in chimeric avian limb buds and its relation to an accessible population of cartilage progenitor cells. Dev Biol 84:440–448
Seed J, Hauschka SD (1984) Temporal separation of the migration of distinct moygenic precursor populations into the developing chick wing bud. Dev Biol 106:383–393
Strudel G (1955) L'action morphogène du tube nerveux et de la corde sur la différenciation des vertèbres et des muscles vertébraux chez l'embryon de Poulet. Arch Anat Microsc Morphol Exp 44:209–235
Toutant M, Montarras D, Fiszman MY (1984) Biochemical evidence for two classes of myoblasts during chick embryonic muscle development. Expl Biol Med 9:10–15
Wachtler F, Jacob M (1986) Origin and development of the cranial skeletal muscles. Bibl Anat 29:24–46
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Kieny, M., Chevallier, A. & Pautou, M.P. Attempt to produce a chick/mouse heteroclass musculature. Roux's Arch Dev Biol 196, 321–327 (1987). https://doi.org/10.1007/BF00395956
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DOI: https://doi.org/10.1007/BF00395956