Abstract
Staphylococcin 1580 killed cells of Staphylococcus aureus Oxford 209P. At low concentrations of staphylococcin the decrease of the viable count as well as the efflux of rubidium ions, and the inhibition of the uptake of amino acids were linearly related to the amount of the bacteriocin used. The killing action could not be reversed by treatment with trypsin, was optimal at pH 7.6 to 7.8, and depended on the incubation temperature. Cells pregrown at 37 C were much more sensitive to staphylococcin 1580 than cells pregrown at 20 C.
The nature of the resistance of various bacteria to staphylococcin may be due to the protection afforded by their cell wall.
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Jetten, A.M., Vogels, G.D. Characteristics of the killing effect of a Staphylococcus epidermidis bacteriocin. Antonie van Leeuwenhoek 40, 177–183 (1974). https://doi.org/10.1007/BF00394565
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DOI: https://doi.org/10.1007/BF00394565