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Reduced chemotaxis of polymorphonuclear leukocytes in sera from patients with rheumatoid arthritis

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Abstract

The chemotaxis of normal leukocytes washed and suspended in Hanks solution is inhibited by addition of serum from patients with definite rheumatoid arthritis as was shown by experiments in which an extract from Proteus mirabilis served as attractant. From a suspension of normal leukocytes to which normal serum had been added, significantly more leukocytes actively moved through a millipore filter toward the attractant than from a suspension of similar leukocytes in serum from patients.

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References

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Authors and Affiliations

  1. De Wever Hospital, Heerlen, the Netherlands

    H. Beeuwkes & A. Bijlsma

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  1. H. Beeuwkes
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  2. A. Bijlsma
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Beeuwkes, H., Bijlsma, A. Reduced chemotaxis of polymorphonuclear leukocytes in sera from patients with rheumatoid arthritis. Antonie van Leeuwenhoek 40, 233–239 (1974). https://doi.org/10.1007/BF00394381

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  • DOI: https://doi.org/10.1007/BF00394381

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