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Elimination of nucleolus organizers in a case of 13/14 Robertsonian translocation

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Summary

A Robertsonian translocation 45,XY, t(13q; 14q) was detected in the leukocyte cultures of a phenotypically normal male. Silver staining technique for nucleolus organizer regions revealed that both acrocentrics involved in the translocation had lost their nucleolus organizers.

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Authors and Affiliations

  1. Department of Biology, Oklahoma Baptist University, 74801, Shawnee, Oklahoma, USA

    James E. Hurley

  2. Department of Biology, The University of Texas System Cancer Center M. D. Anderson Hospital and Tumor Institute, 77030, Houston, Texas, USA

    S. Pathak

Authors
  1. James E. Hurley
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  2. S. Pathak
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Supported in part by Research grant VC-21 from American Cancer Society

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Hurley, J.E., Pathak, S. Elimination of nucleolus organizers in a case of 13/14 Robertsonian translocation. Hum Genet 35, 169–173 (1977). https://doi.org/10.1007/BF00393966

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  • DOI: https://doi.org/10.1007/BF00393966

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