Abstract
Moulds are able to produce extracellular polysaccharide antigens which are heat-stable and almost genus specific. Of 44 different strains of Penicillium 41 (93%) and all 12 strains of Aspergillus tested produced detectable quantities of an immunologically related antigen. Additionally 10 of these 56 strains produced an antigen immunologically related to the antigen produced by the genera Mucor and Fusarium. Immunologically different, but genus-specific antigens were produced by each of the species belonging to the genus Geotrichum, Fusarium, Cladosporium, Mucor and Rhizopus. The antigens produced by Mucor and Rhizopus, however, were immunologically related.
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References
Baretto-Bergter, E., Gorin, P. A. J. & Travessos, L. R. (1981) Cell constituents of mycelia and conidia of Aspergillus fumigatus. Carbohydr. Res. 95: 205–218
Baretto-Bergter, E. M. & Travassos, L. R. (1980) Chemical structure of the D-galacto-D-mannan component from hyphae of Aspergillus spp. Carbohydr. Res. 86: 273–285
Bennet, J. E., Bhattacharjee, A. K. & Glaudemans, P. J. (1985) Galactofuranosyl groups are immunodominant in Aspergillus fumigatus galactomannan. Molecular Immun. 22: 251–254
Gorin, P. A. J. & Spencer, J. F. T (1968) Structural chemistry of fungal polysaccharides. Advan. Carbohyd. Chem. 23: 367–417
Harris, C. M. & Kell, D. B. (1985) The estimation of microbial biomass. Biosensors 1: 17–84
Jarvis, B., Seiter, D. A. L., Ould, A. J. L. & Williams, R. P. (1984) Observations on the enumeration of moulds in food and feeding stuffs. J. Appl. Bacteriol. 55: 325–326
Johnston, I. R. (1965) The composition of the cell wall of Aspergillus niger. Biochem. J. 96: 651–658
Northolt, N. D. (1979) The effect of wateractivity and temperature on the production of some mycotoxins. Thesis. Agricultural University of Wageningen. The Netherlands
Notermans, S. & Heuvelman, C. J. (1985) Immunological detection of moulds in food by using the enzyme-linked immunosorbent assay (ELISA); preparation of antigens. Int. J. Food Microbiol. 2: 247–258
Notermans, S., Heuvelman, C. J., Egmond,H. P. van, Paulsch, W. E. & Besling, J. R. (1986) Detection of mould in food by the enzyme-linked immunosorbent assay. J. Food Prot. in press
Reis, E. & Lehman, P. F. (1979) Galactomannan antigenemia in invasive aspergillosis. Infect. Immun. 25: 357–365
Sakaguchi, O., Yokota, K. & Suruki, M. (1969) Immunochemical and biochemical studies of fungi. XIII: On the galactomannans isolated from mycelia and culture filtrates of several filamentous Fungi. Jap. J. Microbiol. 13: 1–7
Steinbuch, M. & Audran, R. (1969) The isolation of IgG from mammalian sera with the aid of caprylic aid. Arch. Biochem. Biophys. 134: 279–284
Suzuki, S. & Takeda, N. (1975) Serological cross-reactivity of the D-galacto-D-mannans isolated from several pathogenic fungi against anti-Hormodendrum pedrosoi serum. Carbohydr. Res. A 40: 193–197
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Notermans, S., Soentoro, P.S.S. Immunological relationship of extra-cellular polysaccharide antigens produced by different mould species. Antonie van Leeuwenhoek 52, 393–401 (1986). https://doi.org/10.1007/BF00393467
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DOI: https://doi.org/10.1007/BF00393467