Summary
The anti-tumor activity of amygdalin (NSC 251222), commercially known as Laetrile, was investigated using P388 lymphocytic leukaemia and P815 mast-cell leukaemia in BDF1 mice. Doses varying from 200 mg/kg to 2,000 mg/kg were used following the days 1 and 5 and days 1,5 and 9 schedules. Despite treatment with high doses of amygdalin there was no prolongation in the life-span of mice bearing either P388 or P815 tumor.
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Chitnis, M.P., Adwankar, M.K. & Amonkar, A.J. Studies on high-dose chemotherapy of amygdalin in murine P388 lymphocytic leukaemia and P815 mast cell leukaemia. J Cancer Res Clin Oncol 109, 208–209 (1985). https://doi.org/10.1007/BF00390359
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DOI: https://doi.org/10.1007/BF00390359