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Mapping of the regulatory type Iα and catalytic β subunits of cAMP-dependent protein kinase and interleukin 1α and 1β in the pig

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Abstract

The genes coding for the regulatory type Iα subunit (PRKAR1A) and the catalytic β subunit (PRKACB) of cAMP-dependent protein kinase and the genes for interleukin 1α (IL1A) and interleukin 1β (IL1B) were localized in the pig by means of radioactive in situ hybridization. PRKAR1A was mapped to 12p1.4 and PRKARB to 6q3.1 → q3.3. The genes for IL1A and IL1B were both assigned to Chromosome (Chr) 3, in the region q1.2 → q1.3 and q1.1 → q1.4, respectively. The cDNA nucleotide sequences of these porcine genes were compared with those of human, mouse, and cattle. The location of the genes was discussed in relation to the position of their homologous loci in these mammalian species.

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Authors and Affiliations

  1. Laboratoire de Génétique Cellulaire, Centre INRA Toulouse, BP 27-31326, Castanet-Tolosan Cedex, France

    C. Mellink, Y. Lahbib-Mansais, M. Yerle & J. Gellin

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  1. C. Mellink
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  2. Y. Lahbib-Mansais
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  3. M. Yerle
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  4. J. Gellin
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Mellink, C., Lahbib-Mansais, Y., Yerle, M. et al. Mapping of the regulatory type Iα and catalytic β subunits of cAMP-dependent protein kinase and interleukin 1α and 1β in the pig. Mammalian Genome 5, 298–302 (1994). https://doi.org/10.1007/BF00389544

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  • DOI: https://doi.org/10.1007/BF00389544

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