Abstract
A transient electric birefringence computerized spectrometer inducing Kerr effect in anisotropically polarizable solutions as DNA has been used to investigate, at ambient temperature, the mechlorethamine-DNA interaction in presence and in absence of the WR-1065 radioprotector. The birefringence, and the time relaxation variations versus drug concentration are reported. An interpretation including DNA electrooptic properties is proposed.
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Mallet, G., Lematre, J. & Vasilescu, D. Interaction of the alkylating agent mechlorethamine with DNA in presence and in absence of the radioprotector WR-1065: A transient electric birefringence study. J Biol Phys 22, 1–14 (1996). https://doi.org/10.1007/BF00383818
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DOI: https://doi.org/10.1007/BF00383818