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Characterization of a mutation conferring radiation sensitivity, ior, located close to the gene coding for deoxycytidine deaminase in Escherichia coli

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Summary

The isolation and characterization of a new mutation conferring radiation sensitivity in Escherichia coli is described. This mutation is located close to the gene coding for deoxycytidine deaminase, in the chromosomal region of the gat operon. It is very sensitive to gamma rays and exhibits a decrease in recombination ability. The expression of radiation sensitivity seems to result from the additive effect of the dcd mutation and another mutation of unknown function.

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Authors and Affiliations

  1. U.E.R. Sciences Pharmaceutiques, 35 chemin des Maraîchers, F-31062, Toulouse Cedex, France

    Anne-Marie Estevenon

  2. Centre de Recherche de Biochimie et Génétique Cellulaires CNRS, 118 route de Narbonne, F-31062, Toulouse Cedex, France

    Bernard Martin & Nicole Sicard

Authors
  1. Anne-Marie Estevenon
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  2. Bernard Martin
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  3. Nicole Sicard
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Communicated by H. Böhme

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Estevenon, AM., Martin, B. & Sicard, N. Characterization of a mutation conferring radiation sensitivity, ior, located close to the gene coding for deoxycytidine deaminase in Escherichia coli . Molec. Gen. Genet. 200, 132–137 (1985). https://doi.org/10.1007/BF00383326

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  • DOI: https://doi.org/10.1007/BF00383326

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