Summary
Measurements of the metabolic stability of ribosomal proteins of exponentially growing Escherichia coli B/r showed that their rate of degradation to free amino acids is zero to within limits of the experimental accuracy of ± 0.7% per hour or ± 0.5% per doubling period.
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References
Davern, C. I., and M. Meselson: The molecular conservation of ribonucleic acid during bacterial growth. J. molec. Biol. 2, 153 (1960).
Maaløe, O., and N. O. Kjeldgaard: Control of macromolecular synthesis. New York: W. A. Benjamin 1966.
McCarthy, B. J.: The effects of magnesium starvation on the ribosome content of Escherichia coli. Biochim. biophys. Acta (Amst.) 55, 880 (1962).
Meselson, M., M. Nomura, S. Brenner, C. Davern, and D. Schlessinger: Conservation of ribosomes during bacterial growth. J. molec. Biol. 9, 696 (1964).
Roberts, R. B., P. H. Abelson, D. B. Cowie, T. T. Bolton, and R. J. Britten: Studies of biosynthesis in E. coli. Carnegie Instu. [Publ. 607, 1963].
Schleif, R.: Control of production of ribosomal protein. J. molec. Biol. 27, 41 (1967).
Willetts, N. S.: Intracellular protein breakdown in growing cells of Escherichia coli. Biochem. J. 103, 462 (1967).
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Schleif, R. The metabolic stability of ribosomal protein. Molec. Gen. Genet. 100, 252–255 (1967). https://doi.org/10.1007/BF00381820
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DOI: https://doi.org/10.1007/BF00381820