Summary
In a geographic correlation study, we explored the possibility that residential exposure to radon in groundwater may be related to cancers other than lung cancer. Measurements of radon in groundwater and 1978–1982 cancer mortality data from North Carolina, USA were used to investigate this relationship. Counties were categorized in two levels of radon exposure according to measured radon concentration and geology. In the lower exposure group (unexposed) county mean radon concentrations ranged from 0–228 pCi/1 (0–8436 Bq/m3), and in the upper group (potentially exposed) the range of county average concentrations was 229–10892 pCi/1 (8473–403004 Bq/m3), (median 1375 pCi/1 (50875 Bq/m3)). Adjusted mortality ratios and 95% confidence intervals were calculated for selected cancers, including leukemias, gastro-intestinal tract cancers, and respiratory tract cancers excluding lung cancer. In contrast to other ecologic studies, we found no consistent association between radon level and cancer mortality.
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References
Aldrich LK, Sasser MK, Conners DA (1975) Evaluation of radon concentration in North Carolina ground water supplies. North Carolina Department of Human Resources, Raleigh, NC 1975
Archer VE (1987) Association of lung cancer mortality with precambrian granite. Arch Environ Health 42:87–91
Axelson O, Edling C, Kling H (1979) Lung cancer and residency — a case referent study on the possible impact of exposure to radon and its daughters in dwellings. Scand J Work Environ Health 5:10–15
Bean JA, Issacson P, Hahne RM, Kohler J (1982) Drinking water and cancer incidence in Iowa. Am J Epidemiol 116:924–932
Brutsaert AT, Norton SA, Hess CT, Williams JS (1981) Geologic and hydrologic factors controlling radon-222 in ground water in Maine. Ground Water 19:407–417
Cothern CR, Marcus WL (1984) Estimating risk for carcinogenic environmental contaminants and its impact on regulatory decision-making. Reg Tox Pharm 4:265–274
Cross FT, Harley NH, Hoffman W (1985) Health effects and risks from 222Rn in drinking water. Health Phys 48:649–670
deVilliers AJ, Windish JP, de N. Brent F, Hollywood B, Walsh C, Fisher JW, Parsons WD (1971) Mortality experience of the community and of the fluorospar mining employees at St. Lawrence, Newfoundland. Occup Health Rev 22 1–15
Dunning DE, Bernard SR, Walsh PJ, Killough CG, Pleasant JC (1979) Estimates of internal dose equivalent to 22 target organs for radionuclides occurring in routine releases from fuel-cycle facilities. Vol 2. Oak Ridge National Laboratory, NUREG/CR-0150, Vol 2. ORNL/NUREG/TM-190/V2
Edling C, Kling H, Axelson O (1984) Radon in homes — a possible cause of lung cancer. Scand J Work Environ Health 10:25–34
Fleischer RL (1986) A possible association between lung cancer and a geological outcrop. Health Phys 50:823–827
Hess CT, Weiffenbach CV, Norton SA (1983) Environmental radon and cancer correlations in Maine. Health Phys 45:339–348
Hess CT, Michel J, Horton TR, Prichard HM, Coniglio WA (1985) The occurrence of radioactivity in public drinking water supplies in the United States. Health Phys 48:553–586
Howe GR, Nair RC, Newcombe HB, Miller AB, Abbatt JD (1986) Lung cancer mortality (1950–1980) in relation to radon daughter exposure in a cohort of workers at the Eldorado Beaverlodge uranium mine. JNCI 77:357–362
Hursh JB, Morken DA, Davis TP, Lovaas A (1965) The fate of radon ingested by man. Health Phys 11:465–468
Kahlos H, Asikainen M (1980) Internal radiation doses from radioactivity of drinking water in Finland. Health Phys 30:108–111
Kleinbaum DG, Kupper LL, Morgenstern H (1982) Epidemiologic research. Lifetime Learning Publications, Belmont, California
Lees REM Steel R, Roberts JH (1987) A case-control study of lung cancer relative to domestic radon exposure. Int J Epid 16:7–12
Loomis DP (1987) Radon-222 concentration and aquifer lithology in North Carolina. Ground Water Monitoring Rev 7:33–40
Lundin FE, Lloyd JW, Smith EM, Archer VE, Holaday DA (1969) Mortality of uranium miners in relation to radiation exposure, hard-rock mining and cigarette smoking — 1950 through September 1967. Health Phys 16:571–578
Lyman GH, Lyman CG, Johnson W (1985) Association of leukemia with radium groundwater contamination. JAMA 254:621–626
Miettinen OS (1972) Standardization of risk ratios. Am J Epid 96:383–388
National Council on Radiation Protection and Measurements (1984) Instrumentation and monitoring methods for radiation protection. Report No. 78, Bethesda, Md
Nero AV (1983) Indoor radiation exposure from 222Rn and its daughters: A review of the issue. Health Phys 45:277–288
Nero AV, Schwehr MB, Nazaroff WW, Revzan KL (1986) Distribution of airborne radon-222 concentrations in U.S. homes. Science 234:992–997
O'Brien TR, Decoufle P, Rhodes PH (1987) Leukemia and groundwater contamination (letter). JAMA 257:317
Pohl E, Pohl-Ruling J (1980) Dose distribution in the human organism due to incorporation of radon and decay products as a base for epidemiological studies. In: Clemente GF, Nero AV, Steinhäusler F, Wrenn ME (eds) Proceedings of the Specialist Meeting on the Assessment of Radon and Daughter Exposure and Related Biological Effects. RD Press, Salt Lake City, pp 84–91
Radford EP, St. Claire Renard KG (1984) Lung cancer in swedish iron miners exposed to low doses of radon daughters. N Engl J Med 310:1485–1494
Sevc J, Kunz E, Placek V (1976) Lung cancer in uranium miners and long-term exposure to radon daughter products. Health Phys 30:433–437
Soumela M, Kahlos H (1972) Studies on the elimination rate and the radiation exposure after ingestion of 222Rn rich water. Health Phys 23:641–652
Tanner AB (1964) Radon migration in the ground: a review. In: Adams AS, Lowder WM (eds) The natural radiation environment. University of Chicago Press, Chicago
U.S. Environmental Protection Agency, Environmental Radiation Data Report 28, EPA 520/1-83-602, 1982
Waxweiler RJ, Roscoe RJ, Archer VE, Thun MJ, Wagoner JK, Lundin FE (1981) Mortality follow-up through 1977 of the white underground uranium miners cohort examined by the United States Public Health Service. In: Gomez M (ed) Radiation hazards in mining: International Conference. Society of Mining Engineers of American Institute of Mining, Metalurgical and Petroleum Engineers, Inc, New York, pp 823–830
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Collman, G.W., Loomis, D.P. & Sandler, D.P. Radon-222 concentration in groundwater and cancer mortality in North Carolina. Int. Arch Occup Environ Heath 61, 13–18 (1988). https://doi.org/10.1007/BF00381602
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DOI: https://doi.org/10.1007/BF00381602