Summary
Exposure of rabbits to 0.5 ppm hydrogen cyanide alone or in combination with 200 ppm carbon monoxide for one and four weeks or combined exposure to 0.5 ppm hydrogen cyanide, 200 ppm carbon monoxide, and 5 ppm nitric oxide for two weeks did not cause morphological changes in lungs, pulmonary arteries, coronary arteries, or aorta. The need for selective toxicity studies with tobacco smoke constituents is stressed.
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Supported by a grant from the Forschungsgesellschaft Rauchen und Gesundheit, Hamburg, Federal Republic of Germany
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Hugod, C. Effect of exposure to 0.5 ppm hydrogen cyanide singly or combined with 200 ppm carbon monoxide and/or 5 ppm nitric oxide on coronary arteries, aorta, pulmonary artery, and lungs in the rabbit. Int. Arch Occup Environ Heath 44, 13–23 (1979). https://doi.org/10.1007/BF00381205
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DOI: https://doi.org/10.1007/BF00381205