Summary
Cyclohexane in environmental air, alveolar air, and blood, and urinary cyclohexanol were determined in shoe factory workers occupationally exposed to cyclohexane. All the parameters studied correlated well with each other. The mean alveolar cyclohexane corresponded to 78% of the environmental cyclohexane. Blood cyclohexane corresponded to 53–78% of alveolar cyclohexane concentration. Urinary cyclohexanol corresponded to 0.1–0.2% of the cyclohexane absorbed.
The results suggest that biological monitoring of cyclohexane via alveolar air and urine can be reliably used in the evaluation of occupational exposure. It is likely that the urinary cyclohexanol test, from the practical viewpoint, represents the simplest way of monitoring cyclohexane exposure in industrial plants.
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Perbellini, L., Brugnone, F. Lung uptake and metabolism of cyclohexane in shoe factory workers. Int. Arch Occup Environ Heath 45, 261–269 (1980). https://doi.org/10.1007/BF00380789
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DOI: https://doi.org/10.1007/BF00380789