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Non-mutagenicity of some wood-related compounds in the bacterial/microsome plate incorporation and microsuspension assays

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Summary

Seven commercially available wood-related compounds have been tested for mutagenicity by the use of the Ames and fluctuation test-systems. All compounds were found to be non-mutagenic. Among these compounds, 2,6-dimethoxy-p-benzoquinone showed a very weak and questionable mutagenic activity against Salmonella typhimurium TA 100. In this connection, probable causes of nasal adenocarcinoma of woodworkers are briefly discussed.

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Abbreviations

CA:

coniferyl alcohol

DMBQ:

2,6-dimethoxy-1,4-benzoquinone

DPT:

deoxypodophyllotoxin

SP:

scopoletin

TA:

tannic acid

TCA:

3,4,5-trimethoxy-cinnamic acid

VA:

vanilic acid

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  1. Institut für Hygiene and Arbeitsmedizin, Universitätsklinikum (GHS), D-4300, Essen, Germany

    E. Mohtashamipur & K. Norpoth

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  1. E. Mohtashamipur
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  2. K. Norpoth
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Mohtashamipur, E., Norpoth, K. Non-mutagenicity of some wood-related compounds in the bacterial/microsome plate incorporation and microsuspension assays. Int Arch Occup Environ Heath 54, 83–90 (1984). https://doi.org/10.1007/BF00378731

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  • DOI: https://doi.org/10.1007/BF00378731

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