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Erythrocyte osmotic resistance during acute hypothermia in awake unrestrained rats

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  • Heart, Circulation, Respiration and Blood; Environmental and Exercise Physiology
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Summary

Erythrocyte osmotic fragility and plasma ionic composition were studied in rats subjected to acute hypothermia. A decrease in osmotic fragility and a significant increase in plasma magnesium and total phosphorus were observed in blood from hypothermic rats in relation to control. A decrease in erythrocyte osmotic fragility from hypothermic animals was observed when the test was performed at 37°C, whereas osmotic fragility was unaltered if the test was carried out at body temperature. This could be interpreted as an adaptative response to counteract the opposite effect on erythrocyte osmotic fragility observed at low temperature ‘in vitro’.

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References

  1. Aloni B, Eitan A, Livne A (1977) The erythrocyte membrane site for the effect of temperature on osmotic fragility. Biochim Biophys Acta 465: 46–53.

    Google Scholar 

  2. Maclean GS (1980) Blood viscosity of two mammalian hibernators: Spermophilus tridecemlineatus and Tamias striatus. Physiol Zool 54: 122–131.

    Google Scholar 

  3. Mcarthur MD, Jourdan ML, Wang LCH (1992) Prolonged stable hypothermia: effect on blood gases and pH in rats and ground squirrels. Am J Physiol 262: R190-R197.

    Google Scholar 

  4. Mosior M, Bialas WA, Gomulkiewicz J, Bobrowska M, Komorowska M, Koter M (1984) Effect of phosphate ions on osmotic fragility and membrane fluidity of bovine erythrocytes. Stud Biophys 99: 117–126.

    Google Scholar 

  5. Parpart AK, Lorenz PB, Parpart ER, Gregg JR, Chase AM (1947) The osmotic resistance (fragility) of human red cells. J Clin Invest 26: 636–640.

    Google Scholar 

  6. Peinado VI, Viscor G, Palomeque J (1992) Erythrocyte osmotic fragility in artyodactilids mammals: Relationships with plasma osmolality and red cell dimensions. Comp Haem Int 2: 45–50.

    Google Scholar 

  7. Richieri GV, Mel HC (1985) Temperature effects on osmotic fragility, and the erythrocyte membrane. Biochim Biophys Acta 813: 41–50.

    Google Scholar 

  8. Tongyai S, Rayssiguier Y, Motta C, Gueux E, Maurois P, Heaton FW (1989) Mechanism of increased erythrocyte membrane fluidity during magnesium deficiency in weanling rats. Am J Physiol 257: C270-C276.

    Google Scholar 

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Authors and Affiliations

  1. Unidad de Fisiología, Departamento de Bioquímica y Fisiología, Universidad de Barcelona, Avda. Diagonal, 645, E-08071, Barcelona, Spain

    V. I. Peinado, V. Alfaro, J. Palomeque, L. Palacios & G. Viscor

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  1. V. I. Peinado
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  2. V. Alfaro
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  3. J. Palomeque
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  4. L. Palacios
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  5. G. Viscor
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Peinado, V.I., Alfaro, V., Palomeque, J. et al. Erythrocyte osmotic resistance during acute hypothermia in awake unrestrained rats. Pflügers Arch. 424, 555–557 (1993). https://doi.org/10.1007/BF00374923

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  • DOI: https://doi.org/10.1007/BF00374923

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