Abstract
Bladder wall mechanoreceptors are essential elements in micturition and continence reflexes. While they have been described as tension receptors, their response to bladder wall deformation has always been characterised in terms of pressure. The firing patterns of 10 bladder wall mechanoreceptors were determined during bladder distensions at a natural and a much faster rate. In all units firing rate was higher at any given pressure at the slower bladder distension rate. This inverse rate dependence was reduced when firing rate was related to a derived measure of bladder wall tension and abolished when multi-fibre recordings were used. We conclude that it is important to incorporate volume effects in studies of continence control systems.
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References
Bahns E, Halsband U, Janig W (1987) Responses of sacral visceral afferents from the lower urinary tract, colon and anus to mechanical stimulation. Pflügers Arch 410:296–303
Fall M, Lindstrom S, Mazieres L (1990) A bladder-to-bladder cooling reflex in the cat. J Physiol (Lond) 427:281–300
Habler HJ, Janig W, Koltzenburg M (1990) Activation of unmyelinated afferent fibres by mechanical stimuli and inflammation of the urinary bladder in the cat. J Physiol (Lond) 425:545–562
Iggo A (1955) Tension receptors in the stomach and the urinary bladder. J Physiol (Lond) 128:593–607
Klevmark B (1974) Motility of the urinary bladder in cats during filling at physiological rates. I. Intravesical pressure patterns studied by a new method of cystometry. Acta Physiol Scand 90:565–577
Klevmark B (1977) Motility of the urinary bladder in cats during filling at physiological rates. II. Effects of extrinsic denervation on intramural tension and on intravesical pressure patterns. Acta Physiol Scand 101:176–184
Klevmark B (1980) Motility of the urinary bladder in cats during filling at physiological rates. III. Spontaneous rhythmic bladder contractions in the conscious and anesthetized animal. Influence of distension and innervation. Scand J Urol Nephrol 14:219–224
Lamb H (1943) Statics-including hydrostatics and the elements of the theory of elasticity, 3rd edn. University Press, Cambridge
Satchell PM (1991) The initiation of non-micturating contractions in the feline bladder. Acta Physiol Scand 143:339–344
Satchell PM, Vaughan C (1988) Hypogastric nerve activity to the feline bladder during slow filling. J Auton Nerv Syst 25:41–47
Vaughan C, Satchell PM (1991) Rate of bladder distension and hypogastric nerve activity in the cat. J Auton Nerv Syst 34:129–138
Vaughan C, Satchell PM (1992) Role of sympathetic innervation in the feline continence process under natural filling conditions. J Neurophysiol 68:1842–1849
Winter DL (1971) Receptor characteristics and conduction velocities in bladder afferents. J Psychiatr Res 8:225–235
Worden AN, Waterhouse CE, Sellwood EHB (1960) Studies on the composition of normal cat urine. J Small Anim Pract 1:11–23
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Satchell, P., Vaughan, C. Bladder wall tension and mechanoreceptor discharge. Pflügers Arch. 426, 304–309 (1994). https://doi.org/10.1007/BF00374786
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DOI: https://doi.org/10.1007/BF00374786