Abstract
Nine women with primary ovarian failure, who were having their artificial menstrual cycles manipulated with physiological levels of estrogen and high doses of progesterone, were entered into the study. They filled in urinary symptom questionnaires and had urodynamic investigations in the two phases of treatment: estrogen and progesterone, and estrogen alone. The number of voids per 24 hours was significantly greater in the progesterone phase, as was the end filling pressure on cystometry. This is the first report in the literature of the effects of high-dose progesterone on the lower urinary tract.
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Cutner, A., Burton, G., Cardozo, L.D. et al. Does progesterone cause an irritable bladder?. Int Urogynecol J 4, 259–261 (1993). https://doi.org/10.1007/BF00372731
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DOI: https://doi.org/10.1007/BF00372731