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The effect of 1,25(OH)2-vitamin D3 on Langerhans cells and contact hypersensitivity in mice

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References

  1. Bhalla AK, Amento EP, Krane SM (1986) Differential effects of 1,25-dihydroxyvitamin D3 on human lymphocytes and monocyte/macrophages: inhibition of interleukin-2 and augmentation of interleukin-1 production. Cell Immunol 98: 311–322

    Google Scholar 

  2. Bittiner B, Bleehen SS, Macneil S (1991) 1α,25(OH)2 vitamin D3 increases intracellular calcium in human keratinocytes. Br J Dermatol 124: 230–235.

    Google Scholar 

  3. Breathnach SM, Katz SI (1985) Cell-mediated immunity in cutaneous disease. Hum Pathol 17: 161–167

    Google Scholar 

  4. Elmets CA, Bergstresser PR, Tigelaar RE, Wood PJ, Streilein JW (1983) Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation. J Exp Med 158: 781–794

    Google Scholar 

  5. Guo ZP, Okamoto H, Imamura S (1991) The optimal conditions of adenosine nucleotide phosphatase staining for Langerhans cell of human, guinea pig and mouse. Acta Dermatol (Kyoto) 86: 215–218

    Google Scholar 

  6. Hashimoto K, Matsumoto K, Higashiyama M, Nishida Y, Yoshikawa K (1990) Growth-inhibitory effects of 1,25-dihydroxyvitamin D3 on normal and psoriatic keratinocytes. Br J Dermatol 123: 93–98

    Google Scholar 

  7. Heufler C, Koch F, Schuler G (1988) Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells. J Exp Med 167: 700–705

    Google Scholar 

  8. Holick MF (1989) Will 1,25-hydroxyvitamin D3, MC 903, and their analogues herald a new pharmacologic era for the treatment of psoriasis? Arch Dermatol 125: 1692–1697

    Google Scholar 

  9. Hosomi J, Hosoi J, Abe E, Suda T, Kuroki T (1983) Regulation of terminal differentiation of cultured mouse epidermal cells by l,25-dihydroxyvitamin D3. Endocrinology 113: 1950–1957

    Google Scholar 

  10. Kato T, Rokugo M, Terui T, Tagami H (1986) Successful treatment of psoriasis with topical application of active vitamin D3 analogue, 1α,24-dihydroxycholecalciferol. Br J Dermatol 115: 431–433

    Google Scholar 

  11. Kim TA, Golden P, Ullrich SE, Kripke ML (1990) Immunosuppression by factors released from UV-irradiated epidermal cells: selective effects on the generation of contact and delayed hypersensitivity after exposure to UVA or UVB radiation. J Invest Dermatol 94: 26–32

    Google Scholar 

  12. Lemire JM, Adams JS, Sakai R, Jordan SC (1984) 1α, 1,25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells. J Clin Invest 74: 657–661

    Google Scholar 

  13. Matsumoto K, Hashimoto K, Kiyoki M, Yamamoto M, Yoshikawa K (1990) Effect of l,24R-dihydroxyvitamin D3 on the growth of human keratinocytes. J Dermatol (Japan) 17: 97–103

    Google Scholar 

  14. Morimoto S, Kumahara Y (1985) A patient with psoriasis cured by 1α-hydroxyvitamin D3. Med J Osaka Univ 35: 51–54

    Google Scholar 

  15. Morimoto S, Yoshikawa K (1989) Psoriasis and vit D3. Arch Dermatol 125: 231–234.

    Google Scholar 

  16. Morimoto S, Yoshikawa K, Kozuka T, Kitano Y, Imanaka S, Fukuo K, Koh E, Kumahara Y (1986) An open study of vitamin D3 treatment in psoriasis vulgaris. Br J Dermatol 115: 421–429

    Google Scholar 

  17. Smith EL, Walworth ND, Holick MF (1986) Effect of 1,25-dihydroxyvitamin D3 on the morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown in serum-free conditions. J Invest Dermatol 86: 709–714

    Google Scholar 

  18. Smith EL, Pincus SH, Donovan L, Holick MF (1988) A novel approach for the evaluation and treatment of psoriasis. J Am Acad Dermatol 19: 516–528

    Google Scholar 

  19. Staberg B, Roed-Petersen J, Meene T (1989) Efficacy of topical treatment in psoriasis with MC 903, a new Vitamin D analogue. Acta Derm Venereol (Stockh.) 69: 147–150

    Google Scholar 

  20. Stingl G, Katz SI, Clement L, Geen I, Shevach EM (1978) Immunologic functions of Ia-bearing epidermal Langerhans cells. J Immunol 121: 2005–2013

    Google Scholar 

  21. Stumpf WE, Sar M, Reid FA, Tanaka Y, DeLuca HF (1979) Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid. Science 206: 1188–1190

    Google Scholar 

  22. Tsoukas CD, Provvedine DM, Manolagas SC (1984) 1,25-dihydroxyvitamin D3, a novel immunoregulatory hormone. Science 224: 1438–1440

    Google Scholar 

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Authors and Affiliations

  1. Department of Dermatology, Faculty of Medicine, Kyoto University, Sakyo-ku, 606, Kyoto, Japan

    Z. Guo, H. Okamoto & S. Imamura

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  1. Z. Guo
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  2. H. Okamoto
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  3. S. Imamura
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Guo, Z., Okamoto, H. & Imamura, S. The effect of 1,25(OH)2-vitamin D3 on Langerhans cells and contact hypersensitivity in mice. Arch Dermatol Res 284, 368–370 (1992). https://doi.org/10.1007/BF00372042

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  • DOI: https://doi.org/10.1007/BF00372042

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