Abstract
Cultured human keratinocytes were incubated in the presence of glycolipids (GM1, asialoGM1, glucosylceramide and galactosylceramide) added to the medium at a concentration of 10−5 M. All of them became associated with the cells, but in different amounts depending on the type of glycolipid and on the time in culture. GM1- and asialoGM1-treated keratinocytes developed a resistance to peroxidative stress induced by FeSO4/H2O2 treatment. These results suggest that these exogenously added glycolipids could play a role as eutrophic, repairing and protective agents for the epidermis.
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Varani, I., Terzaghi, A., Donati, L. et al. Protective effect of some exogenous glycolipids on human cultured keratinocytes against lipid peroxidation. Arch Dermatol Res 286, 481–483 (1994). https://doi.org/10.1007/BF00371576
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DOI: https://doi.org/10.1007/BF00371576