Skip to main content
Log in

Comparative analysis of calcium gluconate and sodium gluconate techniques for the production of gluconic acid by Aspergillus niger

  • Originals
  • Published:
Bioprocess Engineering Aims and scope Submit manuscript

Abstract

Sodium gluconate and calcium gluconate methods are important techniques available for gluconic acid fermentation. The comparative analysis of these fermentations has been addressed using Aspergillus niger. The techniques are equally influenced by the spores age in slant growth, inoculum level in germination and production media, different levels of Fe, Cu, Zn and Mn. Sodium gluconate method is promising with respect to lesser time for slant age (3 d) and lesser time of fermentation (6 d) compared to the calcium gluconate method (slant age — 6 d, and time of fermentation — 7 d).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Das, A.; Kundu, P. N.: Microbial production of gluconic acid. J. Sci. Ind. Res. 46 (1987) 307–311

    Google Scholar 

  2. Sawyer, D. T.: Metal gluconate complexes. Chem. Rev. 64 (1964) 633–643

    Google Scholar 

  3. Milsom, P. E.; Meers, J. L.: Gluconic and itaconic acids. In: Comprehensive Biotechnol. (M. Moo-Young, Ed.) Pergamon Press Ltd., Vol. 3, pp. 681–700, 1985

  4. Rao, D. S.; Babu, P. S. R.; Satyanarayana, M.: Technology of gluconic acid production. J. Ind. Chem. Engr. (Communicated)

  5. Dirkx, J. M. H.; van der Baan, H. S.: The oxidation of glucose with platinum on carbon as catalyst. J. Catalysis 67 (1981) 1–13

    Google Scholar 

  6. Laane, C.; Pronk, W.; Franssen, M.; Veeger, C.: Use of bioelectrochemical cell for synthesis of (bio)chemicals. Enzyme Microb. Technol. 6 (1984), 165–168

    Google Scholar 

  7. Gastrock, E. A.; Porges, N.: Gluconic acid production on pilot-plant scale. Ind. Eng. Chem. 30 (7) (1938) 782–789

    Google Scholar 

  8. Paterson, S. L.; Fane, A. G.; Fell, C. J. D.; Chun, U. H.; Rogers, P. L.: Sorbitol and gluconate production in a hollow fibre membrane reactor by immobilized Zymomonas mobilis. Biocatalysis 1 (1988) 217–229

    Google Scholar 

  9. van Huynh, N.; Decleire, M.; Voets, A. M.; Motte, J. C.; Monseur, X.: Production of gluconic acid from whey hydrolysate by Gluconobacter oxydans. Process Biochem. Feb. (1986) 31–32

  10. Hartmeier, W.; Heinrichs, A.: Membrane enclosed alginate beads containing Gluconobacter cells and molecular dispersed catalase. Biotechnol. Letters 8 (1986) 567–572

    Google Scholar 

  11. Oosterhuis, N. M. G.; Groesbeek, N. M.; Olivier, A. P. C.; Kossen, N. W. F.: Scale-down aspects of the gluconic acid production. Biotechnol. Letters 5 (1983) 141–146

    Google Scholar 

  12. Kundu, P. N.; Das, A.: Calcium gluconate production by a non-conventional method. Biotechnol. Letters 4 (1982) 365–368

    Google Scholar 

  13. Blom, R. H.; Pfeifer, V. F.; Moyer, A. J.; Traufler, D. H.; Conway, H. F.: Sodium gluconate production — fermentation with Aspergillus niger. Ind. Eng. Chem. 44 (2) (1952) 435–440

    Google Scholar 

  14. Moyer, A. J.; Wells, P. A.; Stubbs, J. J.; Herrick, H. T.; May, O. E.: Gluconic acid production. Ind. Eng. Chem. 29 (1937) 777–781

    Google Scholar 

  15. Röhr, M.; Kubicek, C. P.; Kominek, J.: Gluconic acid: In: Biotechnology, Vol. 3, Rehm, H. J. and Reed, G. (Eds.). Verlag Chemie, Weinheim, pp. 455–465, 1983

    Google Scholar 

  16. Shah, D. N.; Kothari, R. M.: Fermentative production of injectable-grade calcium gluconate. Biotechnol. Progress 7 (1991) 67–69

    Google Scholar 

  17. Tsay, G. S.; To, K. Y.: Citric acid production using immobilized conidia of Aspergillus niger TMB 2022. Biotechnol. Bioengg. 29 (1987) 297–304

    Google Scholar 

  18. Jaksa, I.; Gyuran, J.; Nemeth, S.; Trischler, F.; Udvardy-Nagy, I.: Enhancement of gluconic acid formation during fermentation. Hung. Teljes HU 28 (1983) 770

    Google Scholar 

  19. Miller, G. L.: Use of dinitrosalicylic acid reagent for determination of reducing sugar. Anal. Chem. 31 (1959) 426–429

    Google Scholar 

  20. Lien, Jr., O. G.: Determination of gluconolactone, galactonolactone, and their free acids by the hydroxamate method. Anal. Chem. 31 (8) (1959) 1363–1366.

    Google Scholar 

  21. Heinrich, M.; Rehm, H. J.: Formation of gluconic acid at low pH-values by free and immobilized Aspergillus niger cells during citric acid fermentation. European J. Appl. Microbiol. Biotechnol. 15 (1982) 88–92

    Google Scholar 

  22. Kundu, S.; Panda, T.; Majumdar, S. K.; Guha, B. K.; Bandyopadhyay, K. K.: Pre treatment of Indian cane molasses for increased production of citric acid. Biotechnol. Bioeng. 26 (1984) 1114–1121

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Subba Rao, D., Panda, T. Comparative analysis of calcium gluconate and sodium gluconate techniques for the production of gluconic acid by Aspergillus niger. Bioprocess Engineering 8, 203–207 (1993). https://doi.org/10.1007/BF00369830

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00369830

Keywords

Navigation