Abstract
Evidence is presented for the existence of teratocarcinoma transplantation antigens (Gt) encoded within the H-2 complex and present also on adult tissues. It has not been possible to separate these Gt loci from H-2 by recombination, and Gt factors map to each end of the H-2 complex. Previous reports indicating separation of all Gt loci from H-2 are reinterpreted. One class of such apparent recombinants has been shown to result from the outgrowth of tumor variants in mice of resistant genotype.
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Johnson, L.L., Clipson, L.J., Dove, W.F. et al. Teratocarcinoma transplantation antigens are encoded in the H-2 region. Immunogenetics 18, 137–145 (1983). https://doi.org/10.1007/BF00368542
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DOI: https://doi.org/10.1007/BF00368542