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Elective whole-lung irradiation in osteosarcoma treatment: appearance of bilateral breast cancer in two long-term survivors

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Abstract

The effect of “prophylactic” lung radiation in preventing pulmonary metastasis was studied in a subset of patients with osteosarcoma. Benefit was not noted. Thirteen of the irradiated patients in the treatment group were females; in 2 of the 13, bilateral breast cancer developed approximately 15 years later. Radiation administered to the breast of an adolescent female carries a considerable risk of causing breast cancer.

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Authors and Affiliations

  1. Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA

    J. C. Ivins M.D., W. F. Taylor Ph.D. & L. E. Wold M.D.

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  1. J. C. Ivins M.D.
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  2. W. F. Taylor Ph.D.
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  3. L. E. Wold M.D.
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Ivins, J.C., Taylor, W.F. & Wold, L.E. Elective whole-lung irradiation in osteosarcoma treatment: appearance of bilateral breast cancer in two long-term survivors. Skeletal Radiol 16, 133–135 (1987). https://doi.org/10.1007/BF00367761

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  • DOI: https://doi.org/10.1007/BF00367761

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