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Dependence of steroid 1(2)-dehydrogenation on the C-17 side chain during cholesterol metabolism by immobilized Mycobacterium fortuitum

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Abstract

1(2)-Dehydrogenation of 4-cholestene-3-one by immobilized Mycobacterium fortuitum NRRL B-8153 and free growing Mycobacterium sp. NRRL B-3805 and Micromonospora chlacea MTCC 329 depended on the nature of the C-17 side chain. The 1(2)-dehydrogenation did not appear to occur before C-17-side-chain cleavage of the 4-cholestene-3-one.

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S. Patil is and A. Srivastava was with the School of Life Sciences, Devi Ahilya Vishwavidyalaya. Vigyan Bhawan, Khandwa Road Campus, Indore-452 001, India. A. Srivastava is now with the Shripati Singhania R&D Centre. J. K. Pharmaceuticals. 13th Mile Stone. Mathura Road, Faridabad (Haryana) 121 003, India.

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Srivastava, A., Patil, S. Dependence of steroid 1(2)-dehydrogenation on the C-17 side chain during cholesterol metabolism by immobilized Mycobacterium fortuitum . World Journal of Microbiology & Biotechnology 11, 284–286 (1995). https://doi.org/10.1007/BF00367099

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  • DOI: https://doi.org/10.1007/BF00367099

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