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Histochemistry of the pancreatic islets in golden hamster Mesocricetus auratus waterhouse 1839

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Summary

The histological picuture of the Langerhans' islets in hamster pancreas is quite similar to that in white rat pancreas, i.e. the B-cells are located in the middle of the islet, while the A-cells in its periphery. Very often the argyrophil cells (D-cells) are located between the A- and B-cells forming a peculiar “barrier”.

The histochemical studies reveal differences between the endocrine tissue and exocrine parenchyma. In general, the islet cells are richer in enzymes, as compared with the acini. The histochemical characteristic of hamster pancreas is closest to that of white rat pancreas. Like in rat, alkaline phosphomonoesterase reaction is very strong in the A-cells, while G-6-P reaction is negative. But, concerning zinc localization, there are differences between hamster and rat. Zinc reaction is very strong in the peripheral A-cells in white rat pancreas, while in hamster this reaction is much stronger in the B-cells (the reaction is negative in the A-cells).

The D-cells can not be differentiated from the other endocrine pancreatic cells by means of hystochemical studies.

But these studies permit certain conclusion on the possible role of the enzymes and substances investigated in cytophysiology of the islet cells.

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  1. Department of Histology and Embryology, Medical Faculty, Sofia, Bulgaria

    P. E. Petkov, R. Galabova & Chr. Gospodinov

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  2. R. Galabova
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Petkov, P.E., Galabova, R. & Gospodinov, C. Histochemistry of the pancreatic islets in golden hamster Mesocricetus auratus waterhouse 1839. Histochemie 15, 318–332 (1968). https://doi.org/10.1007/BF00366628

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