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The effect of thyroxine and cortisol on some dehydrogenases and lysosomal enzymes activities in rat pineal cultures

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A histoenzymologic investigation was made concerning the effects of variable doses of thyroxine, cortisol, growth hormone, testosterone propionate and stilboestrol on some oxydo-reducing and lysosomal enzymes activity in rat pineal cell cultures. The thyroxine stimulated predominantly the enzymes of Krebs and Emhden-Meyerhoff cycles and the lipid metabolism. The cortisol stimulated the aryl-sulphatase only. No effect was shown by the pituitary growth and sex hormones. By means of hystoenzymologic techniques two pinealocytes types were in vitro identified: round (basophile) highly active cells and polyedric (chief) cells with lesser enzymatic activity.

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Milcu, S.M., Petrescu, R. & Tasca, C. The effect of thyroxine and cortisol on some dehydrogenases and lysosomal enzymes activities in rat pineal cultures. Histochemie 15, 312–317 (1968). https://doi.org/10.1007/BF00366627

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