Summary
Two yeast DNA fragments carrying the URA 1 gene have been isolated. URA 1 mRNA levels were measured in wild-type yeast and ppr 1 (constitutive for DHOdehase synthesis) strains. Results favour the hypothesis that ppr 1 increases the transcription of URA 1. The corresponding E. coli PYR D gene has also been cloned.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bach ML, Lacroute F, Botstein D (1979) Proc Natl Acad Sci USA 76:386–390
Bolivar F Rodriguez RL, Greene PJ, Betlach MC, Heynecker HL, Boyer HW, Crosa JH, Falcow S (1977) The circular restriction map of pBR 322. In: Bukhari AI, Shapiro JA, Adhya SL (eds.) DNA insertion elements, plasmids and episomes. Cold Spring Harbor, New York, p 686
Bostian KA, Lemire JM, Cannon LE, Halvorson HO (1980) Proc Nat Acad Sci USA 77:4504–4508
Chevallier MR, Bloch JC, Lacroute F (1980) Gene 11:11–19
Clewell DB, Heninski DR (1969) Proc Natl Acad Sci USA 62:1159–1166
Clewell DB (1972) J Bacteriol 110:667–676
Clowes RC, Hayes W (1968) In: Experiments in microbial genetics, p. 187. Wiley, New York
Cohen SN, Chiang ACY, Hsu L (1972) Proc Nat Acad Sci USA 69:2110–2114
Gillespie D, Spiegelman S (1965) J Mol Biol 12:829–842
Goodman HM, MacDonald RJ (1979) Cloning of hormone genes. In: Wu RD (ed) Methods in enzymology, vol 68. Academic Press, London, New York, p 75
Hinnen A, Hicks JB, Fink GR (1978) Proc Nat Acad Sci USA 75:1929–1933
Karibian D (1978) Dihydroorotate dehydrogenase. In: Hoffee PA, Jones ME (eds) Methods in enzymology, vol LI. Academic Press, London New York, p 58
Lacroute F (1968) J Bacteriol 95:824–842
Loison G, Losson R, Lacroute F (1980) Curr Genet 2:39–44
Losson R, Lacroute F (1979) Proc Natl Acad Sci USA 76:5134–5137
Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ (1951) J Biol Chem 193:265–275
Rigby PWJ, Dieckman M, Rhoades C, Berg P (1971) J Mol Biol 113:237–251
Struhl K, Stinchomb DT, Scherer S, Davis RW (1979) Proc Natl Acad Sci USA 76:1035–1039
Sutcliffe GN (1978) Nucl Acids Res 5:2721–2728
Southern EM (1975) J Mol Biol 98:503–517
Waldron C, Lacroute F (1975) J. Bacteriol. 122:855–865
Zitomer SZ, Montgomery DL, Nichols DL, Hall BD (1979) Proc Natl Acad Sci USA 76:3627–3631
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Loison, G., Jund, R., Nguyen-Juilleret, M. et al. Evidence for transcriptional regulation of dihydroorotic acid dehydrogenase in Saccharomyces cerevisiae . Current Genetics 3, 119–123 (1981). https://doi.org/10.1007/BF00365715
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00365715