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Drei neue Nickelenzyme aus anaeroben Bakterien

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Abstract

Until recently nickel was not considered to be an element of biological importance. Nutritional studies have shown, however, that many eucaryotic and procaryotic organisms are dependent on the transition metal for growth. Four enzymes are presently known to contain nickel: urease from plants and from bacteria; methyl CoM reductase from methanogenic bacteria; all “uptake” hydrogenases investigated so far; and carbon monoxide dehydrogenase from anaerobic bacteria. The prosthetic group of the methyl CoM reductase has been identified as a nickel tetrapyrrole, the structure of which has been elucidated.

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References

  1. Thauer, R.K., Diekert, G., Schönheit, P.: TIBS 5, 304 (1980)

    Google Scholar 

  2. Dixon, N.B., et al.: J. Am. Chem. Soc. 97, 4130, 4131 (1975)

    Google Scholar 

  3. Fishbein, W.N., et al.: Fed. Proc. 35, 1643 (1976)

    Google Scholar 

  4. Polacco, J.C.: Plant Physiol. 59, 827 (1977)

    Google Scholar 

  5. Thauer, R.K., Fuchs, G.: Naturwissenschaften 66, 89 (1979)

    Google Scholar 

  6. Balch, W.E., et al.: Microbiol. Rev. 43, 260 (1979)

    Google Scholar 

  7. Schönheit, P., Moll, J., Thauer, R.K.: Arch. Microbiol. 123, 105 (1979)

    Google Scholar 

  8. Taylor, C.D., Wolfe, R.S.: J. Biol. Chem. 249, 4879 (1974)

    Google Scholar 

  9. Eirich, L.D., Vogels, G.D., Wolfe, R.S.: Biochemistry 17, 4583 (1978)

    Google Scholar 

  10. Tzeng, S.F., Wolfe, R.S., Bryant, M.P.: J. Bacteriol. 121, 184 (1975)

    Google Scholar 

  11. Daniels, L., et al.: ibid. 132, 118 (1977)

    Google Scholar 

  12. Vogels, G.D., et al.: Zbl. Bakt. Hyg., I. Abt. Orig. C3, 258 (1982)

    Google Scholar 

  13. Diekert, G., Klee, B., Thauer, R.K.: Arch. Microbiol 124, 103 (1980); 127, 273 (1980)

    Google Scholar 

  14. Gunsalus, R.P., Wolfe, R.S.: FEMS Lett. 3, 191 (1978)

    Google Scholar 

  15. Diekert, G., et al.: J. Bacteriol. 148, 459 (1981)

    Google Scholar 

  16. Ellefson, W.L., Whitman, W.B., Wolfe, R.S.: Proc. Nat. Acad. Sci. USA 79, 3707 (1982)

    Google Scholar 

  17. Whitman, W.B., Wolfe, R.S.: Biochem. Biophys. Res. Commun. 92, 1196 (1980)

    Google Scholar 

  18. Diekert, G., Jaenchen, R., Thauer, R.K.: FEBS Lett. 119, 118 (1980)

    Google Scholar 

  19. Diekert, G., et al.: Arch. Microbiol. 128, 256 (1980)

    Google Scholar 

  20. Jaenchen, R., Gilles, H.-H., Thauer, R.K.: FEMS Lett. 12, 167 (1981)

    Google Scholar 

  21. Gilles, H.-H.: Doktorarbeit Univ. Marburg 1982

  22. Jaenchen, R., Diekert, G., Thauer, R.K.: FEBS Lett. 130, 133 (1981)

    Google Scholar 

  23. Pfaltz, A., et al.: Helv. Chim. Acta 65, Fasc. 3, 828 (1982)

    Google Scholar 

  24. Thauer, R.K., Jungermann, K., Decker, K.: Bacteriol. Rev. 41, 100 (1977)

    Google Scholar 

  25. Addams, M.W.W., Mortenson, L.E., Chen, J.S.: Biochim. Biophys. Acta 594, 105 (1981)

    Google Scholar 

  26. Graf, E.G., Thauer, R.K.: FEBS Lett 136, 165 (1981)

    Google Scholar 

  27. Yamasaki, Sh.: J. Biol. Chem. 257, 7926 (1982)

    Google Scholar 

  28. Albracht, S.P.J., Graf, E.G., Thauer, R.K.: FEBS Lett. 140, 311 (1982)

    Google Scholar 

  29. Jacobson, F.S., et al.: J. Biol. Chem. 257, 3385 (1982)

    Google Scholar 

  30. Cammack, R., et al.: FEBS Lett. 142, 289 (1982)

    Google Scholar 

  31. LeGall, J., et al.: Biochem. Biophys. Res. Commun. 106, 610 (1982)

    Google Scholar 

  32. Unden, G., et al.: FEBS Lett. 145, 230 (1982)

    Google Scholar 

  33. Friedrich, C.G., Schneider, K., Friedrich, B.: J. Bacteriol. 152, 42 (1982)

    Google Scholar 

  34. Albracht, S.P.J., et al.: Biochim. Biophys. Acta 681, 330 (1982)

    Google Scholar 

  35. Takakuwa, S., Wall, J.D.: FEMS Lett. 12, 359 (1981)

    Google Scholar 

  36. Partridge, C.D.P., Yates, M.G.: Biochem. J. 204, 339 (1982)

    Google Scholar 

  37. Brandis, A., Thauer, R.K., Stetter, K.O.: Zbl. Bakt. Hyg., I. Abt. Orig. C2, 311 (1981)

    Google Scholar 

  38. Krzycki, J.A., Wolkin, R.H., Zeikus, J.G.: J. Bacteriol. 149, 247 (1982)

    Google Scholar 

  39. Kenealy, W.R., Zeikus, J.G.: ibid. 151, 932 (1982)

    Google Scholar 

  40. Fuchs, G., Stupperich, E.: Arch. Microbiol. 127, 267 (1980)

    Google Scholar 

  41. Fuchs, G., Stupperich, E.: Forum Mikrobiol. 4, 198 (1981)

    Google Scholar 

  42. Brockhaus, R., Förster, G., in: Ullmanns Enzyklopädie der Technischen Chemie, Bd. 11, p. 57. Weinheim: Verlag Chemie 1976

    Google Scholar 

  43. Ljungdahl, L.G., Wood, H.G., in: Vitamin B12, Vol. II, p. 165 (D. Dolphin, ed.). New York: Academic Press 1982

    Google Scholar 

  44. Ljungdahl, L.G., Wood, H.G.: Ann. Rev. Microbiol. 23, 515 (1969)

    Google Scholar 

  45. Diekert, G., Thauer, R.K.: J. Bacteriol. 136, 597 (1978)

    Google Scholar 

  46. Hu, S., Drake, H.L., Wood, H.G.: ibid. 149, 440 (1982)

    Google Scholar 

  47. Diekert, G., Graf, E.-G., Thauer, R.K.: Arch. Microbiol. 122, 117 (1979)

    Google Scholar 

  48. Drake, H.L.: J. Bacteriol. 149, 561 (1982)

    Google Scholar 

  49. Drake, H.L., Hu, S.I., Wood, H.G.: J. Biol. Chem. 255, 7174 (1980)

    Google Scholar 

  50. Drake, H.L., Hu., S.I., Wood, H.G.: ibid. 256, 11137 (1981)

    Google Scholar 

  51. Diekert, G., Thauer, R.K.: FEMS Lett. 7, 187 (1980)

    Google Scholar 

  52. Diekert, G., Ritter, M.: J. Bacteriol. 151, 1043 (1982)

    Google Scholar 

  53. Diekert, G., Ritter, M.: FEBS Lett. (in press)

  54. Meyer, O.: J. Biol. Chem. 257, 1333 (1982)

    Google Scholar 

  55. Kirchgessner, M., Schnegg, A., in: Nickel in the Environment, p. 635 (J. Nriagu, ed.). New York-Chichester-Brisbane-Toronto: Wiley 1980

    Google Scholar 

  56. Diekert, G., Ritter, M.: FEMS Lett. (in press)

  57. Stupperich, E., et al.: FEBS Lett. (eingereicht)

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Authors and Affiliations

  1. Fachbereich Biologie, Mikrobiologie, der Universität, D-3550, Marburg/Lahn

    Rudolf K. Thauer, Astrid Brandis-Heep, Gabriele Diekert, Hans -Harald Gilles, Ernst Günther Graf, Rolf Jaenchen & Peter Schönheit

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  1. Rudolf K. Thauer
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  2. Astrid Brandis-Heep
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  3. Gabriele Diekert
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  4. Hans -Harald Gilles
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  5. Ernst Günther Graf
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  6. Rolf Jaenchen
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  7. Peter Schönheit
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Additional information

Nach einem Vortrag anläßlich der 112. Versammlung der Gesellschaft Deutscher Naturforscher und Ärzte vom 19. bis 22. September 1982 in Mannheim.

Diese Arbeiten wurden durch die Deutsche Forschungsgemeinschaft und durch den Fonds der Chemischen Industrie gefördert.

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Thauer, R.K., Brandis-Heep, A., Diekert, G. et al. Drei neue Nickelenzyme aus anaeroben Bakterien. Naturwissenschaften 70, 60–64 (1983). https://doi.org/10.1007/BF00365498

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