Abstract
Medullary carcinoma of the thyroid (MCT) and pheochromocytoma are APUD tumors. MIBG (Meta Iodo Benzyl Guanidine) uptake by pheochromocytomas is now well known but very few cases of MIBG uptake in sporadic MCT have been described. We report here the two first cases of inherited MCT with MIBG uptake.
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Chamouard P, Jouin H, Varra A, Weill JP, Constantinesco A (1985) Cancer médullaire de la thyroide au cours d'un syndrome de néoplasies endocriniennes multiple de type II B. Fixation de la méta-iodo-benzyl guanidine marquée à l'iode 131. Presse Med 14:1387–1387
Endo K, Shiomi K, Kasagi K, Konishi J, Torizuka K, Nakao K, Tanimura H (1984) Imaging of medullary thyroid cancer with 131I-MIBG. Lancet 2:233–234
Fischer M, Kamanabroo D, Sonderkamp H, Proske T (1984) Scintigraphic imaging of carcinoid tumours with 131I-metaiodobenzylguanidine. Lancet 2:165–165
Hazard JB, Hawk WA, Crile G (1959) Medullary (solid) carcinoma of the thyroid: A clinico-pathologic entity. J Clin Endocrinol Metab 19:152–161
Milhaud G, Tubiana M, Parmentier C, Coutris G (1968) Epithelioma de la thyroide sécrétant de la calcitonine. CR Acad Sci Paris (Série D) 266:608–610
Nakajo M, Shapiro B, Kalff V, Gross MD, Sisson JC, Beierwaltes WH (1983) The normal and abnormal distribution of the adrenomedullary imaging agent m-(I-131)Iodobenzyl guanidine (I-131 MIBG) in man: Evaluation by scintigraphy. J Nucl Med 24:672–682
Pearse AGE (1969) The cytochemistry and ultrastructure of polypeptide human producing cells of the APUD series and the embryologic implication of the concept. J Histochem Cytochem 17:303–313
Sipple JH (1961) The association of pheochromocytoma with carcinoma of the thyroid gland. Am J Med 31:1111–1118
Teruki Sone, Masao Fukunaja, Nobuaki Otsuka, Rikuski Morita, Akiru Muranaka, Shinichi Yanagimoto, Tatsushi Tomomitsu, Hiroki Nakayama, Tanekazu Harada (1985) Metastatic medullary thyroid cancer: Localization with Iodine-131 metaiodoben-zylguanidine. J Nucl Med 26:604–608
Treuner J, Feine V, Neithammer D, Muller-Schaumberg W, Meinke J, Eibach E, Dopfer R, Klingebiel TH, Grumbach ST (1984) Scintigraphic imaging of neuroblastoma with 131I-miodobenzyl guanidine. Lancet 1:333–334
Valk T, Frejer M, Gross M, Sisson J, Wieland M, Swanson D, Mangner T, Beierwaltes W (1981) Spectrum of pheochromocytoma in multiple endocrine neoplasia: A scintigraphic portrayal using 131I-Metaiodobenzylguanidien. Ann Int Med 94:762–767
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Coutris, G., Talbot, J.N., Kabla, G. et al. Uptake of 131I-MIBG by medullary carcinoma of thyroid in familial cases. Eur J Nucl Med 12, 77–79 (1986). https://doi.org/10.1007/BF00364733
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DOI: https://doi.org/10.1007/BF00364733