Skip to main content

Advertisement

Log in

HLA-B27, A dominant restricting element in antiviral responses?

  • Brief Communication
  • Published:
Immunogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Allen, D. J., Rickinson, A. B., Wallace, L. E., Rowe, M., Moss, D. J., and Epstein, M. A.: Stimulation of human lymphocytes with irradiated cells of the autologous Epstein-Barr virus-transformed cell line. II. Cytotoxic response to repeated stimulation. l. Immunol. 67: 141–151, 1982

    Google Scholar 

  • Allouche, M., Owen, J. A., and Doherty, P. C.: Limit-dilution analysis of weak influenza-immune T cell responses associated with H-2Kb and H-2Dd. J. Immunol. 129: 689–693, 1982

    Google Scholar 

  • Biddison, W. E. and Shaw, S.: Differences in HLA antigen recognition by human influenza virus-immune cytotoxic T cells. J. Immunol. 122: 1705–1709, 1979

    Google Scholar 

  • Biddison, W. E., Ward, F. E., Shearer, G. M., and Shaw, S.: The self determinants recognized by human virus-immune T cells can be distinguished from the serologically defined HLA antigens. J. Immunol. 124: 548–552, 1980

    Google Scholar 

  • Biddison, W. E., Shearer, G. M., and Shaw, S.: Influenza virus-specific cytotoxic T cells are restricted by multiple HLA-A3-related self antigens. J. Immunol. 127: 2231–2235, 1981

    Google Scholar 

  • Breunig, M. H., Lucas, C. J., Breur, B. J., Engelsma, M. Y., De Lange, G. G., Dekker, A. J., Biddison, W. E., and Ivanyi, P.: Subtypes of HLA-1327 detected by cytotoxic T lymphocytes and their role in self-recognition. Hum. Immunol. 5: 259–268, 1982

    Google Scholar 

  • Chiba, Y., Tsutsumi, H., Nakao, T., Wakisaka, A., and Aizawa, M.: Human leukocyte antigen-linked genetic controls for T cell-mediated cytotoxic response to mumps virus in humans. Infect. Immun. 35: 600–604, 1982

    Google Scholar 

  • Doherty, P. C., Biddison, W. E., Bennink, J. R., and Knowles, B. B.: Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 haplotype. J. Exp. Med. 148: 534–542, 1978

    Google Scholar 

  • Fleisher, B.: Cloned lines of human cytotoxic T lymphocytes with specificity for influenza virus. J. Immunol. 129: 1731–1735, 1982

    Google Scholar 

  • Fleisher, B. and Kreth, H. W.: Clonal expansion and functional analysis of virus-specific T lymphocytes from cerebrospinal fluid in measles encephalitis. Hum. Immunol. 7: 239–248, 1983a

    Google Scholar 

  • Fleisher, B. and Kreth, H. W.: Clonal analysis of HLA-restricted virus-specific cytotoxic T lymphocytes from cerebrospinal fluid in mumps meningitis. J. Immunol. 130: 2187–2190, 1983b

    Google Scholar 

  • Fukukawa, T., Hirano, T., Sakaguchi, N., Teranishi, T., Tsuyuguchi, I., Nagao, N., Naito, N., Yoshimura, K., Okubo, Y., Tohda, H., and Oikawa, A.: In vitro induction of HLA-restricted cytotoxic T lymphocytes against autologous Epstein-Barr virus transformed B lymphoblastoid cell line. J. Immunol. 126: 1697–1701, 1981

    Google Scholar 

  • Gaston, J. S. H., Rickinson, A. B., and Epstein, M. A.: Epstein-Barr virus-specific cytotoxic T lymphocytes as probes of HLA polymorphism. Heterogeneity of T cell-restricting determinants associated with the serologically defined HLA-A2 antigen. J. Exp. Med. 158: 280–293, 1983a

    Google Scholar 

  • Gaston, J. S. H., Rickinson, A. B., and Epstein, M. A.: Cross-reactivity of self-HLA-restricted Epstein-Barr virus-specific cytotoxic T lymphocytes for allo-HLA determinants. J. Exp. Med. 158: 1804–1821, 1983b

    Google Scholar 

  • Gomard, E., Duprez, V., Reme, T., Colombani, M. J., and Levy, J. P.: Exclusive involvement of H-2Db or H-2Kd product in the interaction between T-killer lymphocytes and syngeneic H-2b or H-2d viral lymphomas. J. Exp. Med. 146: 909–922, 1977

    Google Scholar 

  • Gomard, E., Henin, Y., Colombani, M. J., and Levy, J. P.: Immune response genes control T killer cell response against Moloney tumor antigen cytolysis regulating reactions against the best available H-2 + viral antigen association. J. Exp. Med. 151: 1468–1475, 1980

    Google Scholar 

  • Kress, H. G. and Kreth, H. W.: HLA restriction of secondary mumps-specific cytotoxic T lymphocytes. J. Immunol. 129: 844–848, 1982

    Google Scholar 

  • Kreth, H. W., Kress, L., Kress, H. G., Ott, H. F., and Eckert, G.: Demonstration of primary cytotoxic T cells in venous blood and cerebrospinal fluid of children with mumps meningitis. J. Immunol. 128: 2411–2415, 1982

    Google Scholar 

  • Lucas, C. J., Biddison, W. E., Nelson, D. L., and Shaw, S.: Killing of measles virus-infected cells by human cytotoxic T cells. Infect. Immun. 38: 226–232, 1982

    Google Scholar 

  • McMichael, A. J.: HLA restriction of human cytotoxic T lymphocytes specific for influenza virus. Poor recognition of virus associated with HLA-A2. J. Exp. Med. 148: 1458–1467, 1978

    Google Scholar 

  • McMichael, A. J., Ting, A., Zweerink, H. J., and Askonas, B. A.: HLA restriction of cell-mediated lysis of influenza virus-infected human cells. Nature 270: 524–526, 1977

    Google Scholar 

  • McMichael, A. J., Gotch, F., Cullen, P., Askonas, B. A., and Websters, R. G.: The human cytotoxic T cell response to influenza A vaccination. Clin. Exp. Immunol. 43: 276–284, 1981

    Google Scholar 

  • Moss, D. J., Wallace, L. E., Rickinson, A. B., and Epstein, M. A.: Cytotoxic T cell recognition of Epstein-Barr virus-infected B cells. I. Specificity and HLA restriction of effector cells reactivated in vitro. Eur. J. Immunol. 11: 686–693, 1981

    Google Scholar 

  • Reiss, L. S., Dorf, M. E., Benacerraf, B., and Burakoff, S. J.: Genetic control of the cytolytic T lymphocyte response to influenza viruses: H-2D genes influence the response to H-2K b plus virus. J. Immunol. 128: 2295–2299, 1982

    Google Scholar 

  • Rickinson, A. B., Moss, D. J., Allen, D. J., Wallace, L. E., Rowen, M., and Epstein, M. A.: Reactivation of Epstein-Barr virus-specific cytotoxic T cells by in vitro stimulation with the autologous lymphoblastoid cell line. Int. J. Cancer 27: 593–601, 1981.

    Google Scholar 

  • Sethi, K. K., Stroehmann, I., and Brandis, H.: Cytocytic human T-cell clones expressing Epstein-Barr virus specific and HLA restriction. Immunobiology 160: 274–288, 1981

    Google Scholar 

  • Sethi, K. K., Stroehmann, I., and Brandis, H.: Generation of cytolytic T-cell cultures displaying measles virus specificity and human histocompatibility leukocyte antigen restriction. Infect. Immun. 36: 657–661, 1982

    Google Scholar 

  • Shaw, S., Shearer, G. M., and Biddison, W. E.: Human cytotoxic T-cell responses to type A and type B influenza viruses can be restricted by different HLA antigens. Implications for HLA polymorphism and genetic regulation. J. Exp. Med. 151: 235–244, 1980

    Google Scholar 

  • Simpson, E. and Gordon, R. D.: Responsiveness to H-Y antigen; Ir gene complementation and target cell specificity. Immunol. Rev. 35: 59–75, 1977

    Google Scholar 

  • Sitbon, M., Gomard, E., Hannoun, C., and Levy, J. P.: Anti-influenza human T killer cells present an intertypic activity anti-A and -B type viruses in a secondary reaction in vitro. Clin. Exp. Immunol. 54: 49–58, 1983

    Google Scholar 

  • Slovin, S. F., Schooley, R. T., and Thorley-Lawson, D. A.: Analysis of cellular immune response to EBV by using cloned T cell lines. J. Immunol. 130: 2127–2131, 1983

    Google Scholar 

  • Sugamura, K., Tanaka, Y., and Hinuma, Y.: Establishment of human cytotoxic T-cell lines specific for Epstein-Barr virus-transformed autologous cells. Int. J. Cancer 28: 137–142, 1981

    Google Scholar 

  • Tanaka, Y., Sugamura, K., and Hinuma, Y.: Heterogeneity of allogeneic restriction of human cytotoxic T cell clones specific for Epstein-Barr virus. J. Immunol. 128: 1241–1245, 1982

    Google Scholar 

  • Tsoukas, C. D., Fox, R. I., Slovin, S. F., Carson, D. A., Pellegrino, M., Fong, S., Pasquali, J. L., Ferrone, S., Kung, P., and Vaughan, J. H.: T lymphocyte-mediated cytotoxicity against autologous EBV-genome bearing B cells. J. Immunol. 126: 1742–1746, 1981

    Google Scholar 

  • Von Boehmer, H. and Haas, W.: Distinct Ir genes for helper and killer cells in the cytotoxic responses for H-Y antigen. J. Exp. Med. 150: 1134–1142, 1979

    Google Scholar 

  • Wallace, L. E., Rickinson, A. B., Rowe, M., Moss, D. J., Allen, D. J., and Epstein, M. A.: Stimulation of human lymphocytes with irradiated cells of the autologous Epstein-Barr virus-transformed cell line. I. Virus-specific and non specific components of the cytotoxic response. Cell. Immunol. 67: 129–140, 1982a

    Google Scholar 

  • Wallace, L. E., Rowe, M., Gaston, J. S. H., Rickinson, A. B., and Epstein, M. A.: Cytotoxic T cell recognition of Epstein-Barr virus-infected B cells. III. Establishment of HLA-restricted cytotoxic T cell lines using interleukin 2. Eur. J. Immunol. 12: 1012–1018, 1982b

    Google Scholar 

  • Wallace, L. E., Rickinson, A. B., Rowe, M., and Epstein, M. A.: Epstein-Barr virus-specific cytotoxic T-cell clones restricted through a single HLA antigen. Nature 297: 413–415, 1982c

    Google Scholar 

  • Wallace, L. E., Rickinson, A. B., and Epstein, M. A.: Epstein-Barr virus-specific cytotoxic T-cell clones restricted through a single HLA-A or B antigen. Transplant. Proc. 15: 196–199, 1983

    Google Scholar 

  • Zinkernagel, R. M., Althage, A., Cooper, S., Kreeb, C., Klein, P. A., Septon, B., Flaherty, L., Stimpfling, J., Shreffler, D., and Klein, J.: Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells; mapping to K or D and dominance of unresponsiveness. J. Exp. Med. 148: 592–606, 1978

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gomard, E., Sitbon, M., Toubert, A. et al. HLA-B27, A dominant restricting element in antiviral responses?. Immunogenetics 20, 197–204 (1984). https://doi.org/10.1007/BF00364490

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00364490

Keywords

Navigation