Skip to main content
Log in

Thymic reconstitution of H-2-linked T-cell responses to thyroglobulin or insulin

  • Brief Communications
  • Published:
Immunogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Cohen, I. R. and Talmon, J.: H-2 genetic control of the response of T lymphocytes to insulins. Priming of nonresponder mice by forbidden variants of specific antigenic determinants. Eur. J. Immunol. 10: 284–289, 1980

    Google Scholar 

  • Cohen, I. R., Talmon, J., Lev-Ram, V., and Ben Nun, A.: Immune response genes have a variable influence on the selection of antigenic foreign and self determinants of insulin. Proc. Natl. Acad. Sci. U.S.A. 76: 4066–4072, 1979

    Google Scholar 

  • Grossman, Z. and Cohen, I. R.: A theoretical analysis of the phenotypic expression of immune response genes. Eur. J. Immunol. 10: 633–640, 1980

    Google Scholar 

  • Hedrick, S. M. and Watson, J.: Genetic control of the immune response to collagen. II. Antibody responses in fetal liver restored radiation chimeras and thymus reconstituted F1 hybrid nude mice. J. Exp. Med. 150: 646–652, 1979

    Google Scholar 

  • Keck, K.: Ir gene control of immunogenicity of insulin and A-chain loop as a carrier determinant. Nature 254: 78–79, 1975

    Google Scholar 

  • Keck, K.: Ir gene control of carrier recognition. III. Cooperative recognition of two or more carrier determinants on insulins of different species. Eur. J. Immunol. 7: 811–816, 1977

    Google Scholar 

  • Kruisbeek, A. M., Sharrow, S. O., Mathieson, B. J., and Singer, A.: The H-2 phenotype of the thymus dictates the self-specificity expressed by thymic but not splenic cytotoxic T lymphocyte precursors in thymus engrafted nude mice. J. Immunol. 127: 2168–2176, 1981

    Google Scholar 

  • Lake, J. P., Andrew, M. E., Pierce, C. W., and Braciale, T. J.: Sendai virus specific H-2 restricted cytotoxic T lymphocyte responses of nude mice grafted with allogeneic or semi-allogeneic thymus glands. J. Exp. Med. 152: 1805–1810, 1980

    Google Scholar 

  • Maron, R. and Cohen, I. R.: Mutation of H-2K locus influences susceptibility to autoimmune thyroiditis. Nature 279: 715–716, 1979

    Google Scholar 

  • Maron, R. and Cohen, I. R.: H-2K mutation controls immune response phenotype of autoimmune thyroiditis. Critical expression of mutant gene product in both thymus and thyroid glands. J. Exp. Med. 152: 1115–1120, 1980

    Google Scholar 

  • Maron, R., Klein, J., and Cohen, I. R.: Mutations at the H-2K or H-2D alter immune response phenotype of autoimmune thyroiditis. Immunogenetics 15: 625–627, 1982

    Google Scholar 

  • Nairn, R., Yamaga, K., and Nathenson, S. G.: Biochemistry of the H-2 mutants. Annu. Rev. Genet. 14: 241–277, 1980

    Google Scholar 

  • Press, J. L., Haber, J., and Wortis, H. H.: The H-2 haplotype of a thymus graft influences the Ir gene regulated IgG3, IgG1, IgG2b and IgG2a anti-(T, G)-A--L antibody response of high responder F1 nude mice. J. Immunol. 128: 441–446, 1982

    Google Scholar 

  • Rosenwasser, L. J., Barcinski, M. A., Schwartz, R. H., and Rosenthal, A. S.: Immune response gene control of determinant selection. II. Genetic control of the murine T lymphocyte proliferation response to insulin. J. Immunol. 123: 471–776, 1979

    Google Scholar 

  • Singer, A., Hathcock, K. S., and Hodes, R. J.: Self recognition in allogeneic thymic chimeras. Self recognition by T helper cells from thymus engrafted nude mice is restricted to the thymic H-2 haplotype. J. Exp. Med. 155: 339–344, 1982

    Google Scholar 

  • Tomazic, V., Rose, N. R., and Shreffler, D. C.: Autoimmune murine thyroiditis. IV. Location of genetic control of the immune response. J. Immunol. 112: 965–969, 1974

    Google Scholar 

  • Vladutiu, A. O. and Rose, N. R.: Autoimmune murine thyroiditis relation to histocompatibility (H-2) type. Science 174: 1137–1139, 1971

    Google Scholar 

  • Vladutiu, A. O. and Rose, N. R.: Cellular basis of the genetic control of immune responsiveness to murine thyroglobulin in mice. Cell. Immunol. 17: 106–113, 1975

    Google Scholar 

  • Wick, G., Schwartz, S., and Muller, P. U.: No development of experimental autoimmune thyroiditis in nude mice. Z. Immunol. Forsch. 154: 162–168, 1978

    Google Scholar 

  • Zinkernagel, R. M., Althage, A., and Callahan, G.: Thymic reconstitution of nude F1 mice with one or both parental thymus grafts. J. Exp. Med. 150: 693–697, 1979

    Google Scholar 

  • Zinkernagel, R. M., Althage, A., Waterfield, E., Kindred, B., Welsh, R. M., Callahan, G., and Princetel, P.: Restriction specificities alloreactivity and allotolerance expressed by T cells from nude mice reconstituted with H-2 compatible or incompatible thymus grafts. J. Exp. Med. 151: 376–399, 1980

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Maron, R., Cohen, I.R. Thymic reconstitution of H-2-linked T-cell responses to thyroglobulin or insulin. Immunogenetics 17, 95–100 (1983). https://doi.org/10.1007/BF00364293

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00364293

Keywords

Navigation