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Flow and O2 content of the blood return from the myocardium to the coronary sinus and other cardiac vessels

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Summary

In the anesthetized dog with by-pass of the right ventricle or with total by-pass of the heart, quantitative data were obtained on the distribution of the myocardial venous blood between the coronary sinus and other cardiac vessels and on the O2 content of these two blood fractions. The results of the right heart by-pass experiments confirm that the 60–70% of the coronary venous blood returns from coronary sinus. The progressive rise of the right systolic ventricular pressure increases the amount of blood returning from coronary sinus.

The O2 content of coronary sinus blood is constantly lower than the O2 content of the extracoronary venous blood at all the values of systolic pressure in the right ventricle. The experiments with the total by-pass of the heart show that the distribution of venous blood between the coronary sinus and extracoronary channels and the difference in O2 content between the two coronary bloods do not seem practically influenced by the fact that the two ventricles are working or not.

These results could be explained: first by the fact that in the normal circulatory conditions the O2 consumption of the right ventricle is lower than that of the left ventricle; second by an increased velocity of the blood travelling through the right coronary artery; third there is a direct arterial flow to the right ventricle through the arterio-luminals and arterio-sinusoidals. However the above mentioned hypothesis are not experimentally demonstrated and then further investigations are needed to throw better light on this problem.

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Marchetti, G., Merlo, L. & Noseda, V. Flow and O2 content of the blood return from the myocardium to the coronary sinus and other cardiac vessels. Pflügers Archiv 287, 99–110 (1965). https://doi.org/10.1007/BF00363520

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  • DOI: https://doi.org/10.1007/BF00363520

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