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Pseudofractures in the absence of osteomalacia

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Abstract

The presence of bilateral pseudofractures is generally considered a reliable radiologic diagnostic feature of osteomalacia. We report two women with long-standing bilaterally symmetrical femoral pseudofractures that did not demonstrate the histologic features of osteomalacia upon examination of non-decalcified sections of iliac crest bone. One patient treated empirically for osteomalacia developed evidence of early vitamin D intoxication. We conclude that there is no completely reliable non-invasive diagnostic test for osteomalacia.

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Authors and Affiliations

  1. Department of Medicine, Division of Bone and Mineral Metabolism, The Jewish Hospital of St. Louis, Washington University School of Medicine, St. Louis, Missouri, USA

    Horace M. Perry III M.D., Steven L. Teitelbaum M.D., Louis V. Avioli M.D. & Michael D. Fallon M.D.

  2. Department of Pathology and Laboratory Medicine, The Jewish Hospital of St. Louis, Washington University School of Medicine, St. Louis, Missouri, USA

    Steven L. Teitelbaum M.D. & Michael D. Fallon M.D.

  3. Metabolic Bone Disease Laboratory, Medical College of Georgia, Augusta, Georgia, USA

    Robert S. Weinstein M.D.

Authors
  1. Horace M. Perry III M.D.
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  2. Robert S. Weinstein M.D.
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  3. Steven L. Teitelbaum M.D.
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  4. Louis V. Avioli M.D.
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  5. Michael D. Fallon M.D.
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Perry, H.M., Weinstein, R.S., Teitelbaum, S.L. et al. Pseudofractures in the absence of osteomalacia. Skeletal Radiol 8, 17–19 (1982). https://doi.org/10.1007/BF00361362

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  • DOI: https://doi.org/10.1007/BF00361362

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